Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474734 | 0.86 | CASP3 (0.41) | CASP3CASP7SPHK1DRD2DRD1 | |
| SCHEMBL27031271 | 0.81 | HTR6 (0.47) | CASP3CASP7DRD2DRD1DRD4 | |
| SCHEMBL7481690 | 0.81 | NPC1 (0.47) | CYP2D6 | |
| SCHEMBL7477251 | 0.81 | FKBP1A (0.42) | CASP3CASP7 | |
| SCHEMBL31719332 | 0.79 | HTR6 (0.48) | CASP3CASP7DRD2DRD1DRD4 | |
| SCHEMBL7476087 | 0.78 | MMP1 (0.39) | CASP3CASP7 | |
| SCHEMBL12611406 | 0.78 | ATM (0.45) | CASP3CASP7DRD2DRD1DRD4 | |
| SCHEMBL27031270 | 0.75 | ALDH1A1 (0.44) | CASP3CASP7CYP2D6 | |
| SCHEMBL10725263 | 0.74 | RECQL (0.50) | CYP3A4 | |
| SCHEMBL4193998 | 0.74 | RECQL (0.50) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-6057337-A | USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS | SHISEIDO CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| CN-1231286-A | 1,2-Di-substituted piperidine derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO LTD (JP) | 1999-10-13 | — | — | CN | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |