Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7476087 | 0.91 | MMP1 (0.39) | POLBALDH1A1KCNH2HRH3CASP3 | |
| SCHEMBL7484236 | 0.87 | NPC1 (0.44) | POLBALDH1A1CASP3CASP7FKBP1A | |
| SCHEMBL7477516 | 0.87 | MAPT (0.45) | ALDH1A1HRH3SMN1; SMN2 | |
| SCHEMBL7485723 | 0.86 | FKBP1A (0.40) | POLBALDH1A1CASP3CASP7FKBP1A | |
| SCHEMBL27031270 | 0.81 | ALDH1A1 (0.44) | POLBALDH1A1CASP3CASP7FKBP1A | |
| SCHEMBL7474734 | 0.81 | CASP3 (0.41) | CASP3CASP7CYP2D6CA12CA2 | |
| SCHEMBL9068282 | 0.77 | ALDH1A1 (0.48) | POLBALDH1A1CASP3CASP7CYP2D6 | |
| SCHEMBL9068477 | 0.77 | ALDH1A1 (0.48) | POLBALDH1A1CASP3CASP7CYP2D6 | |
| SCHEMBL8702996 | 0.77 | LMNA (0.44) | POLBALDH1A1 | |
| SCHEMBL7481690 | 0.77 | NPC1 (0.47) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-6057337-A | USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS | SHISEIDO CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |