Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 11/20 | 0.40 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4312693 | 0.82 | SMO (0.44) | SMO | |
| SCHEMBL2640249 | 0.82 | SLC6A7 (0.41) | SMOSLC6A7GFER | |
| SCHEMBL5585876 | 0.80 | DDB1 (0.36) | SMO | |
| SCHEMBL7472925 | 0.79 | HTR2C (0.42) | — | |
| SCHEMBL5573580 | 0.77 | SMO (0.43) | SMOSLC6A7GFER | |
| SCHEMBL20141187 | 0.73 | SMO (0.45) | SMOSLC6A7GRM1SMN1; SMN2KMT2A | |
| SCHEMBL905705 | 0.71 | HTR7 (0.38) | CHRM1 | |
| SCHEMBL20141349 | 0.70 | SMO (0.45) | SMOSLC6A7GRM1SMN1; SMN2KMT2A | |
| SCHEMBL3119867 | 0.70 | SLC6A7 (0.43) | SMOSLC6A7GRM1SMN1; SMN2GFER | |
| SCHEMBL5239428 | 0.69 | GPR119 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178973-A2 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | Pharmacia AB (SE) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000076984-A2 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | BIOVITRUM AB (SE) | 2000-12-21 | — | — | WO | disclosed |