Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473013 | 0.84 | NAAA (0.47) | EPHX2 | |
| SCHEMBL7470756 | 0.84 | HRH3 (0.40) | HRH3NAMPTAKR1C3VNN1KCNH2 | |
| SCHEMBL7480867 | 0.80 | NPSR1 (0.40) | HRH3EPHX2MAPTPOLB | |
| SCHEMBL7482518 | 0.78 | RAB9A (0.45) | NAMPTAKR1C3POLBKMT2A | |
| SCHEMBL7478289 | 0.76 | TP53 (0.47) | HRH3MAPTALDH1A1 | |
| SCHEMBL3345206 | 0.76 | NAMPT (0.44) | HRH3NAMPTAKR1C3VNN1EPHX2 | |
| SCHEMBL771962 | 0.74 | NPC1 (0.49) | HRH3EPHX2FKBP1APOLB | |
| SCHEMBL13873084 | 0.72 | NAMPT (0.42) | HRH3NAMPTAKR1C3VNN1EPHX2 | |
| SCHEMBL1967273 | 0.72 | AKR1C3 (0.47) | NAMPTAKR1C3VNN1POLBL3MBTL1 | |
| SCHEMBL20590901 | 0.72 | AKR1C3 (0.47) | NAMPTAKR1C3VNN1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |