Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 11/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470756 | 0.84 | HRH3 (0.40) | NPSR1 | |
| SCHEMBL7475772 | 0.84 | HRH3 (0.42) | EPHX2 | |
| SCHEMBL7473548 | 0.81 | ACHE (0.40) | NPSR1 | |
| SCHEMBL7477702 | 0.81 | DNM1 (0.41) | NAAAEPHX2NPSR1 | |
| SCHEMBL7472666 | 0.80 | ACHE (0.40) | — | |
| SCHEMBL7480867 | 0.80 | NPSR1 (0.40) | NAAAEPHX1EPHX2NPSR1 | |
| SCHEMBL7479943 | 0.80 | GNAI3 (0.42) | — | |
| SCHEMBL7484148 | 0.80 | KDM4E (0.50) | — | |
| SCHEMBL7481061 | 0.80 | NAAA (0.38) | NAAAEPHX1EPHX2NPSR1 | |
| SCHEMBL7471618 | 0.80 | KDM4E (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-6057337-A | USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS | SHISEIDO CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| CN-1231286-A | 1,2-Di-substituted piperidine derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO LTD (JP) | 1999-10-13 | — | — | CN | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |