Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465422 | 0.90 | HTR7 (0.38) | HTR7HTR1AHRH1DRD3HTR2B | |
| SCHEMBL7470360 | 0.89 | ADRA1D (0.42) | DRD4HTR1ADRD3 | |
| SCHEMBL7469687 | 0.81 | DRD4 (0.44) | DRD4HTR7HTR1AHRH1DRD3 | |
| SCHEMBL7467910 | 0.81 | HTR1A (0.40) | HTR1ADRD3 | |
| SCHEMBL7670715 | 0.78 | KCNH2 (0.56) | HTR7HTR1ADRD3 | |
| SCHEMBL7470315 | 0.77 | HTR1A (0.61) | DRD4HTR7HTR1ADRD3 | |
| SCHEMBL7471947 | 0.77 | DRD2 (0.41) | HTR1A | |
| SCHEMBL7477921 | 0.76 | DRD2 (0.50) | DRD4HTR7HTR1ADRD3 | |
| SCHEMBL7464006 | 0.76 | SIGMAR1 (0.53) | DRD4HTR7HTR1ADRD3HTR2B | |
| SCHEMBL7473274 | 0.75 | DRD2 (0.51) | DRD4HTR1ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755930-B1 | BENZOXAZEPINE DERIVATIVES, SALTS THEREOF, AND DRUGS CONTAINING THE SAME | SUNTORY LTD (JP) | 2002-07-31 | — | — | EP | disclosed |
| US-6337397-B1 | A BENZOXAZEPINE DERIVATIVE FOR TREATMENT OF ANXIETY NEUROSIS, PHOBIAS, OBSESSIVE-COMPULSIVE DISORDERS, SCHIZOPHRENIA, POST-CARDIAC TRAUMA STRESS DISORDERS, DEPRESSION DISORDERS, PSYCHOSOMATIC DISORDERS AND OTHER PSYCHONEUROTIC DISORDERS, | SUNTORY LIMITED (JP) | 2002-01-08 | — | — | US | disclosed |
| US-6187769-B1 | Benzoxazepine derivatives and their salts and medicaments containing the same | SUNTORY LIMITED (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0755930-A1 | BENZOXAZEPINE DERIVATIVES, SALTS THEREOF, AND DRUGS CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1997-01-29 | — | — | EP | disclosed |