Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | MMP9 | P14780 | 3/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7163466 | 0.95 | MMP2 (0.42) | ALOX15HSD17B10MAPK1HTTL3MBTL1 | |
| SCHEMBL7374585 | 0.92 | MMP2 (0.44) | ALOX15HSD17B10MAPK1HTTL3MBTL1 | |
| SCHEMBL7364535 | 0.89 | ALOX15 (0.41) | ALOX15HSD17B10MAPK1HTTL3MBTL1 | |
| SCHEMBL7479990 | 0.88 | HSD17B10 (0.40) | ALOX15HSD17B10MAPK1HTTL3MBTL1 | |
| SCHEMBL7365624 | 0.87 | CASP1 (0.41) | ALOX15HSD17B10MAPK1HTTL3MBTL1 | |
| SCHEMBL7364118 | 0.87 | ALOX15 (0.43) | ALOX15HSD17B10MAPK1HTTL3MBTL1 | |
| SCHEMBL7474783 | 0.85 | ITGB3 (0.44) | ALOX15HSD17B10MAPK1HTTL3MBTL1 | |
| SCHEMBL7164959 | 0.85 | MMP2 (0.51) | IDO1TDO2MMP2MMP9MMP1 | |
| SCHEMBL7479315 | 0.84 | ALOX15 (0.41) | ALOX15HSD17B10MAPK1HTTL3MBTL1 | |
| SCHEMBL7478564 | 0.83 | ALOX15 (0.44) | ALOX15HSD17B10MAPK1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0964856-B1 | BICYCLIC AMINO ACIDS | MERCK PATENT GMBH (DE) | 2002-10-09 | — | — | EP | disclosed |