Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 11/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27583598 | 0.88 | PPARG (0.42) | FLT1KDRPPARGTSHRPPARD | |
| SCHEMBL7473999 | 0.83 | PPARG (0.49) | PPARGTSHR | |
| SCHEMBL7471302 | 0.83 | TSHR (0.43) | FLT1KDRPPARGTSHRPPARD | |
| SCHEMBL7477507 | 0.83 | CA12 (0.46) | FLT1KDRTSHRKDM4EALDH1A1 | |
| SCHEMBL7481379 | 0.82 | ALDH1A1 (0.46) | FLT1KDRTSHRKDM4EALDH1A1 | |
| SCHEMBL27583585 | 0.82 | LMNA (0.47) | FLT1KDRTSHRKDM4EALDH1A1 | |
| SCHEMBL7474367 | 0.80 | MAOA (0.43) | FLT1KDRTSHRKDM4EALDH1A1 | |
| SCHEMBL7482851 | 0.80 | PPARG (0.51) | PPARG | |
| SCHEMBL7477071 | 0.80 | THRA (0.52) | PPARGPPARDPPARAKDM4EMEN1 | |
| SCHEMBL7478282 | 0.79 | TSHR (0.42) | FLT1KDRTSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210343-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | AstraZeneca AB (SE) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001012187-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2001-02-22 | — | — | WO | disclosed |