Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9068477 | 0.89 | ALDH1A1 (0.48) | ALDH1A1TP53ALOX15MAPK1NPSR1 | |
| SCHEMBL9068282 | 0.89 | ALDH1A1 (0.48) | ALDH1A1TP53ALOX15MAPK1NPSR1 | |
| SCHEMBL7485723 | 0.87 | FKBP1A (0.40) | FKBP1AALDH1A1TP53ALOX15MAPK1 | |
| SCHEMBL7481690 | 0.87 | NPC1 (0.47) | TP53MAPT | |
| SCHEMBL18497662 | 0.87 | LMNA (0.44) | FKBP1AALDH1A1TP53ALOX15MAPK1 | |
| SCHEMBL9068328 | 0.86 | ALDH1A1 (0.46) | ALDH1A1TP53ALOX15MAPK1NPSR1 | |
| SCHEMBL7476087 | 0.84 | MMP1 (0.39) | FKBP1AALDH1A1LMNACASP3CASP7 | |
| SCHEMBL27031270 | 0.82 | ALDH1A1 (0.44) | FKBP1AALDH1A1CASP3CASP7POLB | |
| SCHEMBL8702996 | 0.82 | LMNA (0.44) | ALDH1A1NPSR1L3MBTL1LMNAPOLB | |
| SCHEMBL7477416 | 0.81 | S1PR1 (0.47) | CASP3CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-6057337-A | USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS | SHISEIDO CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |