Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7477639 | 0.80 | TSHR (0.51) | KDM4EALDH1A1KMT2ACA1CA9 | |
| SCHEMBL7483897 | 0.79 | F2 (0.45) | KDM4EALDH1A1NPC1NFKB1RAB9A | |
| SCHEMBL7465669 | 0.78 | KDM4E (0.55) | ALOX5IKBKBCHUKKDM4EALDH1A1 | |
| SCHEMBL7475482 | 0.72 | POLB (0.44) | MMP12MMP13ALOX5IKBKBCHUK | |
| SCHEMBL7478027 | 0.69 | ALDH1A1 (0.48) | KDM4EALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL12394316 | 0.69 | HDAC2 (0.58) | MMP12MMP13ALOX5KDM5AKDM4C | |
| SCHEMBL7482853 | 0.69 | HRH3 (0.50) | MMP13KDM4EALDH1A1MEN1NPC1 | |
| SCHEMBL1247877 | 0.69 | ALOX5 (0.57) | MMP12MMP13ALOX5IKBKBCHUK | |
| SCHEMBL7077495 | 0.68 | AHR (0.51) | KDM4EALDH1A1F2 | |
| SCHEMBL7474003 | 0.67 | HRH3 (0.60) | MMP13KDM4EALDH1A1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210343-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | AstraZeneca AB (SE) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001012187-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2001-02-22 | — | — | WO | disclosed |