Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1144526 | 0.82 | GABBR2 (0.44) | ALDH1A1L3MBTL1GAANPY5RFFAR1 | |
| SCHEMBL4033350 | 0.81 | CYP2D6 (0.32) | ALDH1A1L3MBTL1NPY5RNPC1MAPT | |
| SCHEMBL5700881 | 0.69 | MAPT (0.40) | ALDH1A1KDM4ESMN1; SMN2KMT2AMAPT | |
| SCHEMBL5700879 | 0.69 | MAPT (0.40) | ALDH1A1KDM4ESMN1; SMN2KMT2AMAPT | |
| SCHEMBL17772922 | 0.67 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1GAAKDM4EFFAR1 | |
| SCHEMBL26620695 | 0.67 | TRPM8 (0.48) | GAALMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL1144391 | 0.67 | GABBR2 (0.42) | ALDH1A1L3MBTL1GAAFFAR1LMNA | |
| SCHEMBL16689325 | 0.66 | CHRNB2 (0.54) | ALDH1A1L3MBTL1GAAKDM4EFFAR1 | |
| SCHEMBL5698049 | 0.66 | CHRNB2 (0.54) | ALDH1A1L3MBTL1GAAKDM4EFFAR1 | |
| SCHEMBL4567237 | 0.66 | GABBR2 (0.53) | ALDH1A1L3MBTL1GAAFFAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020156111-A1 | Substituted bicyclic compounds | AVENTIS PHARMA LIMITED (GB) | 2002-10-24 | — | — | US | disclosed |
| EP-1177181-A1 | SUBSTITUTED BICYCLIC COMPOUNDS | Aventis Pharma Limited (GB) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000068213-A1 | SUBSTITUTED BICYCLIC COMPOUNDS | AVENTIS PHARMA LIMITED (GB) | 2000-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156111-A1 | Substituted bicyclic compounds | VCAM1, ITGA1, ITGA5 | ALDH1A1 619/4885L3MBTL1 2971/4885GAA 4161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.