Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 8/20 | 0.40 |
| ▸ | GABRD | O14764 | 8/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 8/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 8/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 8/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 8/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 8/20 | 0.40 |
| ▸ | GABRE | P78334 | 8/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 8/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 8/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 8/20 | 0.40 |
| ▸ | GABRQ | Q9UN88 | 8/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7239468 | 0.87 | KDR (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6976085 | 0.87 | KDR (0.51) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7489890 | 0.82 | KDR (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30831882 | 0.81 | GABRA2 (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL239495 | 0.80 | GABRB3 (0.60) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Ammonia Solution, Strong SCHEMBL8425567 | 0.79 | GABRB3 (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL14615157 | 0.79 | GABRB3 (0.55) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2002008 | 0.77 | GABRP (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2003583 | 0.77 | MAPT (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2138287 | 0.77 | GABRP (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846686-B1 | 1-Phenyl-pyrazol derivatives and their use as parasiticidal agents | PFIZER LTD (GB) | 2002-01-09 | — | — | EP | disclosed |
| US-6156782-A | Parasiticidal compounds | PFIZER INC (US) | 2000-12-05 | — | — | US | disclosed |
| US-6069157-A | Parasiticidal compounds | PFIZER INC. (US) | 2000-05-30 | — | — | US | disclosed |
| EP-0846686-A1 | 1-Phenyl-pyrazol derivatives and their use as parasiticidal agents | Pfizer Limited (GB) | 1998-06-10 | — | — | EP | disclosed |