Tert-Butanol

Tert-Butanol

SCHEMBL748090

CC(C)(C)O.O

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Tert-Butanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tert-Butanol SCHEMBL11102479 1.00 ALDH1A1 (0.42)
Tert-Butanol SCHEMBL4592834 1.00
Tert-Butanol SCHEMBL15348135 1.00 ALDH1A1 (0.42)
Tert-Butanol SCHEMBL27793425 0.94
Tert-Butanol SCHEMBL27784812 0.94
Tert-Butanol SCHEMBL10822057 0.94
Tert-Butanol SCHEMBL28116329 0.94
Tert-Butanol SCHEMBL6131619 0.94
Tert-Butanol SCHEMBL28208487 0.94
Tert-Butanol SCHEMBL282 0.93

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117105877-A Preparation method of 1,4,8, 11-tetraazacyclotetradecane 山东新时代药业有限公司 2023-11-24 CN claimed
CN-111978520-B Polyethylene glycol monomethyl ether-polylactic acid segmented copolymer, polymer micelle medicine and preparation method 丽珠医药集团股份有限公司 2023-06-23 CN claimed
CN-110294686-A αThe environment-friendly preparation method thereof of -one amide 苏州大学 2019-10-01 CN claimed
CN-106866507-B A kind of synthetic method for tieing up not Buddhist nun 武汉博诚恒瑞医药科技有限公司 2019-08-02 CN claimed
CN-108689869-A The synthetic method of (2E) -4- methylamino -2- butenoate hydrochlorates 苏州市贝克生物科技有限公司 2018-10-23 CN claimed
CN-105130933-B A kind of method for preparing 3 substitution coumarans 苏州大学 2017-10-10 CN claimed
CN-107108650-A It is used as the substituted nitroimidazole of 1,2,3 triazole, 1 ylmethyl, 2,3 dihydro, 2 methyl 6 simultaneously [2,1 b] oxazoles and preparation method thereof of anti-mycobacteria agent 印度科学工业研究所 2017-08-29 CN claimed
CN-106866507-A A kind of synthetic method for tieing up not Buddhist nun 武汉博诚恒瑞医药科技有限公司 2017-06-20 CN claimed
CN-104478920-B A kind of peroxy-silane coupling agent and preparation method thereof 齐齐哈尔大学 2017-05-31 CN claimed
CN-106674155-A Enantioselective synthesis method of chiral (3Z, 9Z)-6, 7-epoxy octadecadiene 安徽农业大学 2017-05-17 CN claimed
WO-2011004387-A2 PROCESS FOR THE PREPARATION OF DEXLANSOPRAZOLE POLYMORPHIC FORMS MATRIX LABORATORIES LTD (IN) 2011-01-13 WO claimed
EP-4748838-A1 BROAD SPECTRUM ANTI-CANCER COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-27 EP disclosed
US-12630527-B2 Broad spectrum anti-cancer compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-19 US disclosed
EP-4739669-A1 SODIUM CHANNEL BLOCKERS Novartis AG (CH) 2026-05-13 EP disclosed
US-12509470-B2 Antiviral heterocyclic compounds ENANTA PHARMACEUTICALS, INC. (US) 2025-12-30 US disclosed
EP-1081137-A1 Selective inhibitors of aggrecanase in osteoarthritis treatment Pfizer Products Inc. (US) 2001-03-07 EP disclosed
CN-1195472-A Pesticide compositions ROHM & HAAS (US) 1998-10-14 CN disclosed
WO-1998018805-A2 SUGAR DERIVATIVES AS SIALYL LEWIS X MIMETICS NOVARTIS AG (CH) 1998-05-07 WO disclosed
WO-1998008854-A2 SUGAR DERIVATIVES AS SIALYL LEWIS X MIMETICS NOVARTIS AG (CH) 1998-03-05 WO disclosed
EP-0100592-A1 Eye ointments and a method for their production FISONS plc (GB) 1984-02-15 EP disclosed