Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL750906 | 0.94 | TP53 (0.39) | MAPTTP53SRCSMN1; SMN2MEN1 | |
| SCHEMBL747958 | 0.93 | TP53 (0.38) | MAPTTP53SRCSMN1; SMN2MEN1 | |
| SCHEMBL748289 | 0.88 | SRC (0.39) | SRCKMT2APTGER2LMNANPC1 | |
| SCHEMBL745530 | 0.87 | HDAC1 (0.41) | SRCMEN1KMT2ASLC13A5NPC1 | |
| SCHEMBL748197 | 0.87 | SRC (0.36) | MAPTTP53SRCSMN1; SMN2LMNA | |
| SCHEMBL748241 | 0.87 | LPAR1 (0.36) | MAPTTP53SRCKMT2APTGER2 | |
| SCHEMBL747722 | 0.86 | ESRRG (0.41) | MAPTTP53SRCSMN1; SMN2LMNA | |
| SCHEMBL749993 | 0.86 | LPAR1 (0.39) | MAPTSRCSMN1; SMN2MEN1KMT2A | |
| SCHEMBL751065 | 0.86 | SRC (0.38) | MAPTTP53SRCSMN1; SMN2MEN1 | |
| SCHEMBL748116 | 0.85 | SRC (0.39) | SRCLMNASLC13A5HDAC6GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049493-B1 | COMPOUNDS SUITABLE AS MODULATORS OF HDL | CADILA HEALTHCARE LTD (IN) | 2012-03-21 | — | — | EP | claimed |