Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 11/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6740643 | 0.75 | ITGB1 (0.40) | TRPM8 | |
| SCHEMBL5091415 | 0.73 | NNMT (0.46) | MAPTRAB9APOLB | |
| SCHEMBL7081677 | 0.73 | NNMT (0.46) | MAPTRAB9APOLB | |
| SCHEMBL5801185 | 0.72 | KMT2A (0.50) | MAPTRAB9A | |
| SCHEMBL27552110 | 0.72 | MAPT (0.40) | MAPTRAB9AP2RX7SMN1; SMN2KCNA5 | |
| SCHEMBL7669220 | 0.70 | JAK2 (0.46) | MAPTRAB9APKMPOLB | |
| SCHEMBL4798192 | 0.70 | TRPM8 (0.44) | MAPTRAB9ATRPM8SMN1; SMN2POLB | |
| SCHEMBL6742389 | 0.69 | TRPM8 (0.40) | MAPTRAB9ATRPM8SMN1; SMN2GLA | |
| SCHEMBL4802020 | 0.69 | TRPM8 (0.43) | MAPTRAB9ATRPM8SMN1; SMN2POLB | |
| SCHEMBL29954427 | 0.69 | MAPT (0.35) | MAPTRAB9AKCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089989-A1 | INHIBITORS OF ALPHA4BETA1 MEDIATED CELL ADHESION | PHARMACIA & UPJOHN COMPANY (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067230-A1 | INHIBITORS OF α4β1 MEDIATED CELL ADHESION | PHARMACIA & UPJOHN COMPANY (US) | 1999-12-29 | — | — | WO | disclosed |