Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | FPR1 | P21462 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7485173 | 1.00 | PIN1 (0.46) | PIN1ALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL7489855 | 0.88 | PIN1 (0.46) | PIN1ALDH1A1L3MBTL1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL7478353 | 0.88 | PIN1 (0.45) | PIN1ALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL7490792 | 0.82 | L3MBTL1 (0.47) | PIN1ALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL7480434 | 0.82 | AURKA (0.47) | ALDH1A1L3MBTL1KDM4EKMT2A | |
| SCHEMBL7485673 | 0.82 | L3MBTL1 (0.44) | PIN1ALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL7479564 | 0.81 | L3MBTL1 (0.46) | PIN1ALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL7421962 | 0.79 | PIN1 (0.35) | PIN1ALDH1A1L3MBTL1ACSS2 | |
| SCHEMBL7478946 | 0.79 | ACSS2 (0.39) | PIN1ALDH1A1L3MBTL1ACSS2 | |
| SCHEMBL7490827 | 0.79 | ACSS2 (0.42) | ALDH1A1L3MBTL1KDM4ELMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000020400-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATING HEPATITIS C INFECTIONS | AXYS PHARMACEUTICALS, INC. (US) | 2000-04-13 | — | — | WO | disclosed |