Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | FPR1 | P21462 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7489855 | 0.87 | PIN1 (0.46) | L3MBTL1ALDH1A1KMT2AFPR1KDM4E | |
| Hydrochloric Acid SCHEMBL7478353 | 0.86 | PIN1 (0.45) | L3MBTL1ALDH1A1KMT2AFPR1KDM4E | |
| SCHEMBL7490827 | 0.84 | ACSS2 (0.42) | L3MBTL1ALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL7490792 | 0.84 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1KMT2AFPR1KDM4E | |
| SCHEMBL7480434 | 0.82 | AURKA (0.47) | L3MBTL1ALDH1A1KMT2AKDM4EAURKA | |
| SCHEMBL7485173 | 0.82 | PIN1 (0.46) | L3MBTL1ALDH1A1KMT2AFPR1KDM4E | |
| SCHEMBL7485199 | 0.82 | PIN1 (0.46) | L3MBTL1ALDH1A1KMT2AFPR1KDM4E | |
| SCHEMBL7479564 | 0.80 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1KMT2AFPR1KDM4E | |
| SCHEMBL7069754 | 0.78 | NPC1 (0.49) | L3MBTL1KMT2ALMNAMAPTACSS2 | |
| SCHEMBL7421962 | 0.77 | PIN1 (0.35) | L3MBTL1ALDH1A1ACSS2PIN1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000020400-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATING HEPATITIS C INFECTIONS | AXYS PHARMACEUTICALS, INC. (US) | 2000-04-13 | — | — | WO | disclosed |