Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21754357 | 1.00 | CYP2C19 (0.49) | CYP2C19ALDH1A1CYP1A2ACHEKDM4E | |
| SCHEMBL7485649 | 1.00 | CYP2C19 (0.49) | CYP2C19ALDH1A1CYP1A2ACHEKDM4E | |
| SCHEMBL25225372 | 0.87 | ALDH1A1 (0.46) | CYP2C19ALDH1A1CYP1A2ACHEKDM4E | |
| SCHEMBL29187355 | 0.84 | PTPRC (0.51) | CYP2C19ALDH1A1CYP1A2KDM4EHTT | |
| SCHEMBL25272208 | 0.84 | ACHE (0.40) | CYP2C19ALDH1A1CYP1A2ACHEKDM4E | |
| SCHEMBL25690136 | 0.81 | ALDH1A1 (0.46) | CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL8204533 | 0.77 | CYP2D6 (0.49) | CYP2C19ALDH1A1CYP1A2ACHEKDM4E | |
| SCHEMBL23519692 | 0.75 | ALDH1A1 (0.55) | CYP2C19ALDH1A1CYP1A2HTTTDP1 | |
| SCHEMBL2695765 | 0.75 | ALDH1A1 (0.50) | CYP2C19ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL2695763 | 0.75 | ALDH1A1 (0.50) | CYP2C19ALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260000641-A1 | ISOTOPICALLY ENRICHED ANALOGS OF 5,6-METHYLENEDIOXY-2-AMINOINDANE (IMDAI) | TERRAN BIOSCIENCES INC (US) | 2026-01-01 | — | — | US | disclosed |
| US-20230181521-A1 | ISOTOPICALLY ENRICHED ANALOGS OF 5,6-METHYLENEDIOXY-2-AMINOINDANE (MDAI) | TERRAN BIOSCIENCES INC (US) | 2023-06-15 | — | — | US | disclosed |
| US-20230181521-A1 | ISOTOPICALLY ENRICHED ANALOGS OF 5,6-METHYLENEDIOXY-2-AMINOINDANE (MDAI) | TERRAN BIOSCIENCES INC (US) | 2023-06-15 | — | — | US | disclosed |
| US-20230181521-A1 | ISOTOPICALLY ENRICHED ANALOGS OF 5,6-METHYLENEDIOXY-2-AMINOINDANE (MDAI) | TERRAN BIOSCIENCES INC (US) | 2023-06-15 | — | — | US | disclosed |
| WO-2023081895-A1 | ISOTOPICALLY ENRICHED ANALOGS OF 5,6-METHYLENEDIOXY-2-AMINOINDANE (MDAI) | TERRAN BIOSCIENCES, INC. (US) | 2023-05-11 | — | — | WO | disclosed |
| EP-0982305-B1 | Indane-1-ol derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-03-06 | — | — | EP | disclosed |
| US-6153625-A | Indan-1-ol compounds | ADIR ET COMPAGNIE (FR) | 2000-11-28 | — | — | US | disclosed |
| EP-0982305-A1 | Indane-1-ol derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-03-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260000641-A1 | ISOTOPICALLY ENRICHED ANALOGS OF 5,6-METHYLENEDIOXY-2-AMINOINDANE (IMDAI) | DRD2, HTR1D, DRD1 | CYP2C19 493/4885ALDH1A1 1746/4885CYP1A2 853/4885 |
| US-20230181521-A1 | ISOTOPICALLY ENRICHED ANALOGS OF 5,6-METHYLENEDIOXY-2-AMINOINDANE (MDAI) | ECI1, GDI2, GDI1 | CYP2C19 1405/4885ALDH1A1 124/4885CYP1A2 446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.