Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.48 |
| ▸ | CTSL | P07711 | 16/20 | 0.47 |
| ▸ | CTSS | P25774 | 8/20 | 0.47 |
| ▸ | CTSB | P07858 | 6/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7427147 | 0.83 | CTSL (0.46) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7451296 | 0.83 | CTSL (0.47) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7488479 | 0.74 | CTSL (0.52) | CTSKCTSLCTSSCTSBKCNH2 | |
| SCHEMBL6183387 | 0.74 | CTSK (0.60) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7606091 | 0.74 | CTSK (0.60) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4760512 | 0.74 | CTSK (0.78) | CTSKCTSLCTSSCTSBKCNH2 | |
| SCHEMBL4759913 | 0.73 | CTSK (0.78) | CTSKCTSLCTSSCTSBKCNH2 | |
| SCHEMBL7650778 | 0.67 | CTSL (0.59) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6183392 | 0.65 | CTSB (0.49) | CTSKCTSLCTSSCTSBKCNH2 | |
| SCHEMBL4760896 | 0.65 | CTSK (0.72) | CTSKCTSLCTSSCTSBKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001068645-A2 | N-CYANOMETHYLCARBOXAMIDES AND THEIR USE AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-09-20 | — | — | WO | claimed |