Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 15/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.60 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6306908 | 0.88 | CCR2 (0.60) | CCR2ABCB11 | |
| SCHEMBL7246205 | 0.87 | CCR2 (0.49) | CCR2ABCB11 | |
| SCHEMBL7076142 | 0.86 | CCR2 (0.60) | CCR2TRAP1GPR35 | |
| SCHEMBL7247001 | 0.85 | MAPT (0.49) | CCR2ABCB11F10 | |
| SCHEMBL7465471 | 0.83 | SRD5A2 (0.54) | CCR2ABCB11F10 | |
| SCHEMBL7472885 | 0.82 | CCR2 (0.48) | CCR2ABCB11 | |
| SCHEMBL7525789 | 0.81 | ABCB11 (0.49) | CCR2ABCB11 | |
| SCHEMBL6302551 | 0.81 | CCR2 (0.60) | CCR2TRAP1 | |
| SCHEMBL7498811 | 0.81 | CCR2 (0.49) | CCR2ABCB11 | |
| SCHEMBL7455739 | 0.81 | CCR2 (0.57) | CCR2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242075-A4 | INDOLE COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2002-12-04 | — | — | EP | disclosed |
| EP-1242075-A2 | INDOLE COMPOUNDS | SmithKline Beecham Corporation (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001030752-A2 | INDOLE COMPOUNDS FOR TREATING BACTERIAL INFECTIONS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-03 | — | — | WO | disclosed |