Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 3/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.36 |
| ▸ | MARS1 | P56192 | 1/20 | 0.36 |
| ▸ | EIF4E | P06730 | 1/20 | 0.35 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474145 | 0.86 | ALDH1A1 (0.40) | KMOMAPTADCY10SLC34A1TP53 | |
| SCHEMBL7484830 | 0.79 | ADCY10 (0.33) | RORCADCY10MARS1 | |
| SCHEMBL7486295 | 0.79 | ADCY10 (0.37) | RORCMAPTADCY10 | |
| SCHEMBL7688642 | 0.78 | GRM5 (0.36) | ADCY10 | |
| SCHEMBL8569766 | 0.76 | HSD11B1 (0.47) | GRM2KDM4CMAPTHSD11B1SLC34A1 | |
| SCHEMBL9531790 | 0.76 | PTGS2 (0.37) | KMOHSD11B1SLC34A1 | |
| SCHEMBL7490533 | 0.75 | F2 (0.36) | — | |
| SCHEMBL7490538 | 0.75 | F2 (0.36) | — | |
| SCHEMBL8626557 | 0.75 | HSD11B1 (0.38) | GRM2HSD11B1SLC34A1 | |
| SCHEMBL10955444 | 0.74 | P2RX7 (0.42) | MAPTSLC34A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0769008-B1 | PYRAZOLE DERIVATIVES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-05-22 | — | — | EP | disclosed |