Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7489479 | 0.86 | KMO (0.45) | ADCY10KMOMAPTSLC34A1TP53 | |
| SCHEMBL28906210 | 0.82 | ALDH1A1 (0.48) | ALDH1A1ALPLKDM4EGAAHPGD | |
| SCHEMBL8166685 | 0.81 | ADCY10 (0.37) | ALDH1A1ADCY10ALPLKDM4EGAA | |
| SCHEMBL7487729 | 0.81 | MAPT (0.41) | ALDH1A1ADCY10KDM4EGAAMAPT | |
| SCHEMBL8165668 | 0.81 | ADCY10 (0.41) | ALDH1A1ADCY10ALPLKDM4EGAA | |
| SCHEMBL7479123 | 0.77 | LMNA (0.37) | ALDH1A1ADCY10KDM4EMAPT | |
| SCHEMBL7475083 | 0.76 | CA12 (0.48) | ALDH1A1ALPLKDM4EGAAHPGD | |
| SCHEMBL28906201 | 0.75 | ALDH1A1 (0.43) | ALDH1A1CNR1TP53 | |
| SCHEMBL8569766 | 0.73 | HSD11B1 (0.47) | MAPTSLC34A1 | |
| SCHEMBL9531790 | 0.73 | PTGS2 (0.37) | KMOSLC34A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0769008-B1 | PYRAZOLE DERIVATIVES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-05-22 | — | — | EP | disclosed |
| US-6083881-A | Pyrazole derivatives as herbicides | NOVARTIS CORPORATION (US) | 2000-07-04 | — | — | US | disclosed |
| CN-1151733-A | Pyrazole derivatives AS Herbicides | CIBA GEIGY AG (CH) | 1997-06-11 | — | — | CN | disclosed |
| EP-0769008-A1 | PYRAZOLE DERIVATIVES AS HERBICIDES | Novartis AG (CH) | 1997-04-23 | — | — | EP | disclosed |
| WO-1996001254-A1 | PYRAZOLE DERIVATIVES AS HERBICIDES | CIBA-GEIGY AG (CH) | 1996-01-18 | — | — | WO | disclosed |