Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 5/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCND3 | P30281 | 1/20 | 0.31 |
| ▸ | CDK7 | P50613 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | CCNH | P51946 | 1/20 | 0.31 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.31 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10440375 | 0.81 | NAAA (0.33) | NAAA | |
| SCHEMBL8579591 | 0.79 | PPOX (0.38) | NAAA | |
| SCHEMBL10824307 | 0.79 | NAAA (0.33) | XDHNAAA | |
| SCHEMBL7693188 | 0.76 | TRPV4 (0.47) | CYP11B1CYP11B2 | |
| SCHEMBL31134779 | 0.74 | CYP11B1 (0.42) | CYP11B1CYP11B2HSD17B1HSD17B2XDH | |
| SCHEMBL7492449 | 0.74 | CYP11B1 (0.42) | CYP11B1CYP11B2HSD17B1HSD17B2XDH | |
| SCHEMBL6592771 | 0.74 | HSD17B1 (0.33) | CYP11B1CYP11B2HSD17B1HSD17B2XDH | |
| SCHEMBL10545794 | 0.73 | — | — | |
| SCHEMBL6722274 | 0.72 | TRPV4 (0.35) | HSD17B1HSD17B2 | |
| SCHEMBL6114276 | 0.71 | AR (0.36) | XDHSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648772-B1 | 4-Cyanophenyliminoheterocycles | BAYER AG (DE) | 2002-09-04 | — | — | EP | disclosed |
| EP-1164128-A1 | 4-Cyanophenyliminoheterocycles | BAYER AG (DE) | 2001-12-19 | — | — | EP | disclosed |
| US-5756805-A | CHEMICAL INTERMEDIATES FOR HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-05-26 | — | — | US | disclosed |
| EP-0648772-A1 | 4-Cyanophenylheterocycles | BAYER AG (DE) | 1995-04-19 | — | — | EP | disclosed |