Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.47 |
| ▸ | KHK | P50053 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6722274 | 0.84 | TRPV4 (0.35) | TRPV4KHK | |
| SCHEMBL12528259 | 0.81 | AR (0.40) | TRPV4 | |
| SCHEMBL6594425 | 0.81 | TRPV4 (0.47) | TRPV4KHKCYP11B1CYP11B2 | |
| SCHEMBL1725294 | 0.80 | TRPV4 (0.39) | TRPV4KHKCYP11B1CYP11B2 | |
| SCHEMBL1399737 | 0.79 | ABCB11 (0.34) | — | |
| SCHEMBL7490441 | 0.76 | CYP11B1 (0.38) | CYP11B1CYP11B2 | |
| SCHEMBL6651303 | 0.76 | TRPV4 (0.71) | TRPV4KHKCYP11B1CYP11B2 | |
| SCHEMBL7688191 | 0.72 | PGR (0.40) | — | |
| SCHEMBL11552834 | 0.72 | KDM1A (0.36) | — | |
| SCHEMBL546939 | 0.72 | TRPV4 (0.37) | TRPV4KHK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2475647-B1 | ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF | SUZHOU KINTOR PHARMACEUTICALS INC (CN) | 2015-11-04 | — | — | EP | disclosed |
| US-8809550-B2 | Androgen receptor antagonists and uses thereof | SUZHOU KINTOR PHARMACEUTICALS, INC. (CN) | 2014-08-19 | — | — | US | disclosed |
| US-20120172406-A1 | ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF | Tong, Youzhi (CN) | 2012-07-05 | — | — | US | disclosed |
| WO-2011029392-A1 | ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF | TONG YOUZHI (CN) | 2011-03-17 | — | — | WO | disclosed |
| US-6339044-B1 | USEFUL AS HERBICIDES AND INSECTICIDES | BAYER AKTIENGESELLSCHAFT | 2002-01-15 | — | — | US | disclosed |
| EP-1164128-A1 | 4-Cyanophenyliminoheterocycles | BAYER AG (DE) | 2001-12-19 | — | — | EP | disclosed |
| US-5756805-A | CHEMICAL INTERMEDIATES FOR HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-05-26 | — | — | US | disclosed |
| EP-0736014-A1 | N-CYANOARYL NITROGEN HETEROCYCLES WITH SULPHUR-CONTAINING GROUPINGS | BAYER AG (DE) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017391-A1 | N-CYANOARYL NITROGEN HETEROCYCLES WITH SULPHUR-CONTAINING GROUPINGS | BAYER AKTIENGESELLSCHAFT (DE) | 1995-06-29 | — | — | WO | disclosed |
| EP-0648772-A1 | 4-Cyanophenylheterocycles | BAYER AG (DE) | 1995-04-19 | — | — | EP | disclosed |
| US-4138242-A | Novel 2-aryl-2,3,5,6,7,8-hexahydro-3-thioxoimidazo-[1,5-a-]pyridin-1(BaH)-ones as herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172406-A1 | ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF | AR, SHBG, MUSK | TRPV4 825/4885KHK 2104/4885CYP11B1 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.