Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7497110 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7495222 | 0.81 | ACACB (0.48) | MEN1KMT2ANPSR1PPARAMAPT | |
| SCHEMBL7496442 | 0.80 | LMNA (0.40) | TSHRALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7493041 | 0.80 | L3MBTL1 (0.47) | ALDH1A1KMT2ANPC1RAB9APPARA | |
| SCHEMBL7434063 | 0.79 | CES2 (0.43) | TSHRALDH1A1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL7430292 | 0.79 | CYP1A2 (0.49) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL7500101 | 0.79 | NPC1 (0.41) | TSHRALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL7485958 | 0.78 | NPSR1 (0.54) | SMN1; SMN2MEN1KMT2ANPSR1NPC1 | |
| SCHEMBL7500749 | 0.77 | RARB (0.48) | ALDH1A1MEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL7436814 | 0.77 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2NPSR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453003-A | ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS | UMEZAWA HAMAO (JP) | 1984-06-05 | — | — | US | disclosed |
| US-4391986-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-07-05 | — | — | US | disclosed |
| US-4281180-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | disclosed |