Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 3/20 | 0.42 |
| ▸ | ACACA | Q13085 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434063 | 0.91 | CES2 (0.43) | SMN1; SMN2MAPTALDH1A1LMNAHTT | |
| SCHEMBL7496442 | 0.84 | LMNA (0.40) | MAPTALDH1A1LMNAHTTHPGD | |
| SCHEMBL7430292 | 0.83 | CYP1A2 (0.49) | SMN1; SMN2ALDH1A1LMNAACACBNPC1 | |
| SCHEMBL7500101 | 0.83 | NPC1 (0.41) | ALDH1A1HPGDNPC1RAB9AGAA | |
| SCHEMBL7493860 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPTALDH1A1HPGDNPC1 | |
| SCHEMBL7497110 | 0.81 | ALDH1A1 (0.46) | MAPTALDH1A1LMNAACACBNPC1 | |
| SCHEMBL7435408 | 0.81 | ALDH1A1 (0.51) | MAPTALDH1A1ACACBHPGDNPC1 | |
| SCHEMBL7493041 | 0.78 | L3MBTL1 (0.47) | MAPTALDH1A1LMNAACACBACACA | |
| SCHEMBL7437066 | 0.78 | KMT2A (0.51) | SMN1; SMN2MAPTALDH1A1LMNAACACB | |
| SCHEMBL7490643 | 0.78 | KDM4E (0.50) | SMN1; SMN2MAPTLMNAL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453003-A | ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS | UMEZAWA HAMAO (JP) | 1984-06-05 | — | — | US | disclosed |
| US-4391986-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-07-05 | — | — | US | disclosed |
| US-4281180-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | disclosed |