Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7487346 | 0.87 | XDH (0.36) | XDHTRPV1 | |
| SCHEMBL7488208 | 0.80 | KMT2A (0.41) | XDHALDH1A1MAOAKMT2AMEN1 | |
| SCHEMBL3371015 | 0.72 | XDH (0.47) | XDHALDH1A1SCDKMT2AMEN1 | |
| SCHEMBL7495778 | 0.72 | ABL1 (0.43) | ALDH1A1SCDKMT2AMEN1NPC1 | |
| SCHEMBL23367029 | 0.70 | XDH (0.45) | XDHALDH1A1SCDKMT2AMEN1 | |
| SCHEMBL30497064 | 0.68 | LMNA (0.60) | XDHALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL11768743 | 0.68 | LMNA (0.60) | XDHALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL643994 | 0.67 | XDH (0.51) | XDHALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL416843 | 0.66 | KIF11 (0.50) | XDHALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL7999948 | 0.66 | XDH (0.55) | XDHALDH1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1201661-A1 | HETEROAROMATIC RING COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2002-05-02 | — | — | EP | disclosed |