Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.30 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7495774 | 0.87 | XDH (0.43) | XDHTRPV1 | |
| SCHEMBL3370341 | 0.74 | KIF11 (0.45) | XDHGRM5PTPN5 | |
| SCHEMBL7488208 | 0.72 | KMT2A (0.41) | XDH | |
| SCHEMBL2478195 | 0.69 | RORC (0.50) | ADORA2AADORA1CNR2NOTUMPTPN5 | |
| SCHEMBL4305451 | 0.67 | MAOA (0.50) | XDHGRM5IKBKB | |
| SCHEMBL28627082 | 0.66 | MEN1 (0.41) | XDH | |
| SCHEMBL7495778 | 0.64 | ABL1 (0.43) | — | |
| SCHEMBL5711323 | 0.64 | LMNA (0.57) | XDHGRM5 | |
| SCHEMBL307118 | 0.64 | ALDH1A1 (0.45) | XDHGRM5ADORA1CNR1CNR2 | |
| SCHEMBL19154057 | 0.63 | MEN1 (0.46) | XDHGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1201661-A1 | HETEROAROMATIC RING COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2002-05-02 | — | — | EP | disclosed |