Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL6558306 | 0.98 | KIF11 (0.48) | KIF11XDHBACE1NR1H3MEN1 | |
| SCHEMBL23367029 | 0.86 | XDH (0.45) | KIF11XDHBACE1MEN1LMNA | |
| SCHEMBL9989089 | 0.84 | ENPP1 (0.42) | KIF11BACE1NR1H3MAOBCYP1A2 | |
| SCHEMBL30497064 | 0.84 | LMNA (0.60) | XDHMEN1LMNATHRBBLM | |
| SCHEMBL11768743 | 0.84 | LMNA (0.60) | XDHMEN1LMNATHRBBLM | |
| SCHEMBL28922004 | 0.84 | MEN1 (0.41) | XDHNR1H3MEN1LMNATHRB | |
| SCHEMBL23367122 | 0.82 | XDH (0.42) | KIF11XDHBACE1MEN1LMNA | |
| SCHEMBL3371015 | 0.81 | XDH (0.47) | KIF11XDHNR1H3MEN1LMNA | |
| SCHEMBL2478195 | 0.81 | RORC (0.50) | KIF11MAOBALDH1A1KDM4EPOLB | |
| SCHEMBL17840160 | 0.80 | KIF11 (0.68) | KIF11BACE1MAOBALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4578522-A | CHEMICAL INTERMEDIATES FOR BLOOD LIPID CONTROLLING COMPOUNDS | BURROUGHS WELLCOME CO. | 1986-03-25 | — | — | US | claimed |
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | ORSOBIO INC (US) | 2026-03-19 | — | — | US | disclosed |
| CN-116003320-A | Preparation method of phenanthridine compound | 武汉理工大学深圳研究院 | 2023-04-25 | — | — | CN | disclosed |
| US-10654878-B2 | Compounds of phosphinanes and azaphosphinanes, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2020-05-19 | — | — | US | disclosed |
| US-10336743-B2 | Aminopyrimidine kinase inhibitors | Jasco Pharmaceuticals, LLC (US) | 2019-07-02 | — | — | US | disclosed |
| US-20190031693-A1 | COMPOUNDS OF PHOSPHINANES AND AZAPHOSPHINANES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2019-01-31 | — | — | US | disclosed |
| US-10138260-B2 | Compounds of phosphinanes and azaphosphinanes, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2018-11-27 | — | — | US | disclosed |
| EP-3271368-B1 | NOVEL PHOSPHINANE AND AZAPHOSPHINANE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2018-10-31 | — | — | EP | disclosed |
| CN-108495857-A | New phospha cyclohexane class compound and azepine phospha cyclohexane class compound, their preparation method and the Pharmaceutical composition comprising them | 法国施维雅药厂 | 2018-09-04 | — | — | CN | disclosed |
| EP-3271368-A1 | NOVEL PHOSPHINANE AND AZAPHOSPHINANE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier (FR) | 2018-01-24 | — | — | EP | disclosed |
| WO-1997041111-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING 4'-TRIFLUOROMETHYLBIPHENYL-2-CARBOXYLIC ACID [2-(2H-[1,2,4]TRIAZOL-3-YLMETHYL)-1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-YL]-AMIDE | PFIZER INC. (US) | 1997-11-06 | — | — | WO | disclosed |
| US-5432185-A | Treating patients exhibiting acute or chronic ischaemic disorders associated with disorders of microcirculation, without lowering or increasing blood pressure | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-11 | — | — | US | disclosed |
| EP-0451654-B1 | Use of N-alkylated 1,4-dihydropyridine carboxylic acid esters as drugs, new compounds and process for their preparation | BAYER AG (DE) | 1994-09-07 | — | — | EP | disclosed |
| US-5342847-A | Antiischetic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1994-08-30 | — | — | US | disclosed |
| US-5234935-A | Preventing myocardial infarct | BAYER AKTIENGESELLSCHAFT (DE) | 1993-08-10 | — | — | US | disclosed |
| EP-0551663-A1 | Dimethyl 2,6-dimethyl-1n-propyl-4-(4-trifluormethylphenyl)-1,4-dihydro-pyridine-3,5-dicarboxylate, method for its production and its pharmaceutical use | BAYER AG (DE) | 1993-07-21 | — | — | EP | disclosed |
| EP-0451654-A2 | Use of N-alkylated 1,4-dihydropyridine carboxylic acid esters as drugs, new compounds and process for their preparation | BAYER AG (DE) | 1991-10-16 | — | — | EP | disclosed |
| EP-0059983-B1 | SUBSTITUTED BIPHENYL COMPOUNDS FOR USE AS A MEDICAMENT | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-06-11 | — | — | EP | disclosed |
| US-4578522-A | CHEMICAL INTERMEDIATES FOR BLOOD LIPID CONTROLLING COMPOUNDS | BURROUGHS WELLCOME CO. | 1986-03-25 | — | — | US | disclosed |
| EP-0059983-A1 | Substituted biphenyl compounds for use as a medicament | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-09-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | CPT1B, CBR1, MUSK | KIF11 4651/4885XDH 125/4885BACE1 1662/4885 |
| US-10654878-B2 | Compounds of phosphinanes and azaphosphinanes, a process for their preparation and pharmaceutical compositions containing them | TK1, AK1, PHKA1 | KIF11 2778/4885XDH 1074/4885BACE1 3420/4885 |
| US-10138260-B2 | Compounds of phosphinanes and azaphosphinanes, a process for their preparation and pharmaceutical compositions containing them | TK1, AK1, PHKA1 | KIF11 2778/4885XDH 1074/4885BACE1 3420/4885 |
| US-10336743-B2 | Aminopyrimidine kinase inhibitors | PIM1, PIM2, PIM3 | KIF11 3298/4885XDH 2627/4885BACE1 2408/4885 |
| US-20190031693-A1 | COMPOUNDS OF PHOSPHINANES AND AZAPHOSPHINANES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AK1, TK1, PHKA1 | KIF11 2921/4885XDH 949/4885BACE1 3417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.