Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | AKT2 | P31751 | 2/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | SMOX | Q9NWM0 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7495778 | 0.81 | ABL1 (0.43) | KMT2AALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL7495774 | 0.80 | XDH (0.43) | KMT2AALDH1A1KDM4EMEN1MAOA | |
| SCHEMBL7487352 | 0.73 | PBRM1 (0.43) | KMT2AALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL7487346 | 0.72 | XDH (0.36) | XDH | |
| SCHEMBL15832876 | 0.71 | ALDH1A1 (0.58) | ALDH1A1CYP1A2AKT2AKT1KIF11 | |
| SCHEMBL19410797 | 0.71 | KDM4E (0.47) | KMT2AALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL18913698 | 0.69 | ESR1 (0.62) | KMT2AALDH1A1KIF11MAPT | |
| SCHEMBL17725569 | 0.69 | L3MBTL1 (0.54) | KMT2AALDH1A1MEN1AKT2AKT1 | |
| SCHEMBL17725567 | 0.69 | L3MBTL1 (0.54) | KMT2AALDH1A1MEN1AKT2AKT1 | |
| SCHEMBL17725262 | 0.69 | L3MBTL1 (0.54) | KMT2AALDH1A1MEN1AKT2AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1201661-A1 | HETEROAROMATIC RING COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2002-05-02 | — | — | EP | disclosed |