Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | RGS12 | O14924 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylephedrine SCHEMBL338479 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1AOC3GAAADRA2C | |
| Methylephedrine SCHEMBL907777 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1AOC3GAAADRA2C | |
| Methylephedrine SCHEMBL99673 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1AOC3GAAADRA2C | |
| Methylephedrine SCHEMBL338478 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1AOC3GAAADRA2C | |
| Methylephedrine SCHEMBL11959977 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1AOC3GAAADRA2C | |
| Methylephedrine SCHEMBL907677 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1AOC3GAAADRA2C | |
| Methylephedrine SCHEMBL2712293 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1AOC3GAAADRA2C | |
| Methylephedrine SCHEMBL99674 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1AOC3GAAADRA2C | |
| Methylephedrine SCHEMBL8083321 | 0.98 | KDM4E (0.96) | KDM4EALDH1A1AOC3GAAADRA2C | |
| Methylephedrine SCHEMBL68363 | 0.98 | ALDH1A1 (0.96) | KDM4EALDH1A1AOC3GAAADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464297-B1 | PROCESS FOR PREPARATION OF ERIBULIN AND INTERMEDIATES THEREOF | Dr Reddys Laboratories Ltd (IN) | 2023-10-25 | — | — | EP | disclosed |
| WO-2017203459-A1 | PROCESS FOR PREPARATION OF ERIBULIN AND INTERMEDIATES THEREOF | DR. REDDY'S LABORATORIES LIMITED (IN) | 2017-11-30 | — | — | WO | disclosed |
| EP-1218349-A2 | METHOD FOR SELECTIVELY DISSOCIATING CYCLIC CARBOXYLIC ACID ANHYDRIDES | MERCK PATENT GmbH (DE) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001025215-A2 | METHOD FOR SELECTIVELY DISSOCIATING CYCLIC CARBOXYLIC ACID ANHYDRIDES | MERCK PATENT GMBH (DE) | 2001-04-12 | — | — | WO | disclosed |