Methylephedrine

Methylephedrine

SCHEMBL99673

C[C@@H]([C@H](O)c1ccccc1)N(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 1.00
ALDH1A1 P00352 2/20 1.00
AOC3 Q16853 5/20 0.70
GAA P10253 1/20 0.56
ADRA2C P18825 2/20 0.56
ADRA2A P08913 1/20 0.56
LMNA P02545 1/20 0.56
HIF1A Q16665 1/20 0.56
CHRM2 P08172 1/20 0.52
ADRA1A P35348 1/20 0.52
RGS12 O14924 1/20 0.52
GLA P06280 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2D6 P10635 1/20 0.52
CYP2C9 P11712 1/20 0.52
PKM P14618 1/20 0.52
ALOX15 P16050 1/20 0.52
TSHR P16473 1/20 0.52
ALOX12 P18054 1/20 0.52
NFKB1 P19838 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylephedrine SCHEMBL99674 1.00 KDM4E (1.00) KDM4EALDH1A1AOC3GAAADRA2C
Methylephedrine SCHEMBL907777 1.00 KDM4E (1.00) KDM4EALDH1A1AOC3GAAADRA2C
Methylephedrine SCHEMBL7496690 1.00 KDM4E (1.00) KDM4EALDH1A1AOC3GAAADRA2C
Methylephedrine SCHEMBL338479 1.00 KDM4E (1.00) KDM4EALDH1A1AOC3GAAADRA2C
Methylephedrine SCHEMBL2712293 1.00 KDM4E (1.00) KDM4EALDH1A1AOC3GAAADRA2C
Methylephedrine SCHEMBL11959977 1.00 KDM4E (1.00) KDM4EALDH1A1AOC3GAAADRA2C
Methylephedrine SCHEMBL907677 1.00 KDM4E (1.00) KDM4EALDH1A1AOC3GAAADRA2C
Methylephedrine SCHEMBL338478 1.00 KDM4E (1.00) KDM4EALDH1A1AOC3GAAADRA2C
Methylephedrine SCHEMBL8083321 0.98 KDM4E (0.96) KDM4EALDH1A1AOC3GAAADRA2C
Methylephedrine SCHEMBL68363 0.98 ALDH1A1 (0.96) KDM4EALDH1A1AOC3GAAADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4330 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4722714-A1 SIMULTANEOUS ANALYSIS OF FOOD-BORNE DOPING SUBSTANCES USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (VFD: VACCINE FOR FOODBORNE DOPING) Korea Institute of Science and Technology (KR) 2026-04-08 EP claimed
EP-4704839-A2 IMIDAZOLE CONTAINING COMPOUNDS, DERIVATIVES THEREFORE, AND USES THEREOF ALPHERABIO LLC (US) 2026-03-11 EP claimed
US-20250213647-A1 CHEMOKINE RECEPTORS AND ALPHA1 ADRENERGIC RECEPTORS/VASOPRESSIN RECEPTORS 1A HETEROMERS AS DRUG TARGETS FOR DISEASE UNIVERSITY OF SOUTH FLORIDA 2025-07-03 US claimed
EP-3694864-B1 BORONIC ACID DERIVATIVES AND SYNTHESIS THEREOF QPEX BIOPHARMA INC (US) 2025-03-05 EP claimed
WO-2024226608-A2 IMIDAZOLE CONTAINING COMPOUNDS, DERIVATIVES THEREFORE, AND USES THEREOF AGLAEAPHARMA INC. (US) 2024-10-31 WO claimed
WO-2023192319-A1 CHEMOKINE RECEPTORS AND ALPHA1 ADRENERGIC RECEPTORS/VASOPRESSIN RECEPTORS 1A HETEROMERS AS DRUG TARGETS FOR DISEASE UNIVERSITY OF SOUTH FLORIDA (US) 2023-10-05 WO claimed
EP-3322482-B1 TOPICAL CIPROFLOXACIN COMPOSITIONS TAP PHARMACEUTICALS AG (CH) 2023-07-26 EP claimed
WO-2023125519-A1 NEW APPLICATION OF PLANT-DERIVED ALKALINE PHOSPHATASE EXPRESSION PROMOTER 香港科技大学 2023-07-06 WO claimed
CN-115901988-A Construction method of fingerprint of magnolia bark-ephedra decoction, standard fingerprint and application thereof 神威药业集团有限公司 2023-04-04 CN claimed
CN-113621133-B Reversible plasticizing type polyester chip and preparation method thereof 扬州帅帅高分子科技有限公司 2023-03-14 CN claimed
EP-0565301-A1 Prolonged-release liquid type of pharmaceutical preparation ROHTO PHARMACEUTICAL CO., LTD. (JP) 1993-10-13 EP claimed
EP-0311383-B1 MONOCLONAL ANTIBODY TO METHAMPHETAMINE, PREPARATION OF THE SAME, ASSAY METHOD AND ASSAY KIT OF METHAMPHETAMINE UBE INDUSTRIES, LTD. (JP) 1993-10-06 EP claimed
EP-0195329-B1 METHOD FOR THE PREPARATION OF THE (-)-ANTIPODE OF (E)-1-CYCLOHEXYL-4,4-DIMETHYL-3-HYDROXY-2-(1,2,4-TRIAZOL-1-YL)-PENT-1-ENE BAYER AG (DE) 1989-02-08 EP claimed
EP-0035355-B1 MODIFIED ALUMINIUM HYDRIDES, THEIR PREPARATION AND THEIR USE IN REDUCING ACETYLNAPHTHALENE DERIVATIVES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-05-09 EP claimed
US-4418218-A REDUCTION WITH LITHIUM ALUMINUM HYDRIDE AND N-SUBSTITUTED EPHEDRINE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-11-29 US claimed
US-4338255-A Modified lithium aluminum hydrides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-07-06 US claimed
US-4328173-A Resolution of D,L-cis and D,L-trans 2,2-dimethyl-3-(2,2-dihalovinyl)-cyclopropane-1-carboxylic acids and salts thereof ROUSSEL UCLAF (FR) 1982-05-04 US claimed
EP-0035355-A2 Modified aluminium hydrides, their preparation and their use in reducing acetylnaphthalene derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-09-09 EP claimed
US-4285884-A Process for resolution of racemic DL-α-aminocarboxylic acids RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1981-08-25 US claimed
EP-0001821-B1 RESOLUTION OF D,L-ALPHA-AMINO ACIDS AND SALTS USED THEREFOR RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1981-04-29 EP claimed