Methylephedrine

Methylephedrine

SCHEMBL338479

CC([C@H](O)c1ccccc1)N(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 1.00
ALDH1A1 P00352 2/20 1.00
AOC3 Q16853 5/20 0.70
GAA P10253 1/20 0.56
ADRA2C P18825 2/20 0.56
ADRA2A P08913 1/20 0.56
LMNA P02545 1/20 0.56
HIF1A Q16665 1/20 0.56
CHRM2 P08172 1/20 0.52
ADRA1A P35348 1/20 0.52
RGS12 O14924 1/20 0.52
GLA P06280 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2D6 P10635 1/20 0.52
CYP2C9 P11712 1/20 0.52
PKM P14618 1/20 0.52
ALOX15 P16050 1/20 0.52
TSHR P16473 1/20 0.52
ALOX12 P18054 1/20 0.52
NFKB1 P19838 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylephedrine SCHEMBL99674 1.00 KDM4E (1.00) KDM4EALDH1A1AOC3GAAADRA2C
Methylephedrine SCHEMBL907777 1.00 KDM4E (1.00) KDM4EALDH1A1AOC3GAAADRA2C
Methylephedrine SCHEMBL7496690 1.00 KDM4E (1.00) KDM4EALDH1A1AOC3GAAADRA2C
Methylephedrine SCHEMBL2712293 1.00 KDM4E (1.00) KDM4EALDH1A1AOC3GAAADRA2C
Methylephedrine SCHEMBL11959977 1.00 KDM4E (1.00) KDM4EALDH1A1AOC3GAAADRA2C
Methylephedrine SCHEMBL907677 1.00 KDM4E (1.00) KDM4EALDH1A1AOC3GAAADRA2C
Methylephedrine SCHEMBL338478 1.00 KDM4E (1.00) KDM4EALDH1A1AOC3GAAADRA2C
Methylephedrine SCHEMBL99673 1.00 KDM4E (1.00) KDM4EALDH1A1AOC3GAAADRA2C
Methylephedrine SCHEMBL8083321 0.98 KDM4E (0.96) KDM4EALDH1A1AOC3GAAADRA2C
Methylephedrine SCHEMBL68363 0.98 ALDH1A1 (0.96) KDM4EALDH1A1AOC3GAAADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3322482-B1 TOPICAL CIPROFLOXACIN COMPOSITIONS TAP PHARMACEUTICALS AG (CH) 2023-07-26 EP claimed
WO-2026102437-A1 METHODS OF TREATING FRAGILE X SYNDROME USING PDE4 INHIBITORS DART NEUROSCIENCE LLC (US) 2026-05-15 WO disclosed
WO-2026088112-A1 COMBINATION THERAPIES WITH AR-DEGRADING AGENTS AND PSMA-TARGETING RADIOLIGANDS NOVARTIS AG (CH) 2026-04-30 WO disclosed
EP-4698542-A1 2-AZABICYCLO[2.2.1]HEPTANE KRAS INHIBITORS Incyte Corporation (US) 2026-02-25 EP disclosed
EP-4688752-A1 IRHOM2 INHIBITORS AND USES THEREOF New York Society for the Relief of the Ruptured and Crippled, Maintaining the Hospital for Special Surgery (US) 2026-02-11 EP disclosed
EP-4680238-A1 JAK1 PATHWAY INHIBITORS FOR THE TREATMENT OF ASTHMA Incyte Corporation (US) 2026-01-21 EP disclosed
EP-4680607-A1 BICYCLIC UREAS AS KINASE INHIBITORS Incyte Corporation (US) 2026-01-21 EP disclosed
EP-4676927-A1 HETEROCYCLIC COMPOUNDS AS WRN INHIBITORS Synnovation Therapeutics, Inc. (US) 2026-01-14 EP disclosed
WO-2025245087-A1 HETEROCYCLIC COMPOUNDS AS PARG INHIBITORS SYNNOVATION THERAPEUTICS, INC. (US) 2025-11-27 WO disclosed
US-20250228644-A1 METHODS FOR MARKING A TARGET LOCATION FOR A MEDICAL PROCEDURE EPHEMERAL SOLUTIONS, INC. 2025-07-17 US disclosed
US-11241411-B2 Benzonatate modified release solid tablets and capsules TRIS PHARMA, INC. (US) 2022-02-08 US disclosed
WO-2022026645-A1 TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) MELIOR PHARMACEUTICALS I, INC. (US) 2022-02-03 WO disclosed
WO-2017203459-A1 PROCESS FOR PREPARATION OF ERIBULIN AND INTERMEDIATES THEREOF DR. REDDY'S LABORATORIES LIMITED (IN) 2017-11-30 WO disclosed
US-20120083603-A1 HIGH STABILITY POLYIONIC LIQUID SALTS SIGMA-ALDRICH CO. LLC (US) 2012-04-05 US disclosed
US-8097721-B2 polycationic or polyanionic molecules; use as stationary phases in gas chromatography, and as a reagent in electrospray ionization-mass spectrometry (ESI-MS); thermal stability; tris(anion) such as tris(sulfonate) or tris(cation) groups such as imidazolium, pyrrolidinium, ammonium SIGMA-ALDRICH CO. LLC (US) 2012-01-17 US disclosed
US-7772405-B2 3-alkyl-5- (4-alkyl-5-oxo-tetrahydrofutran-2-yl) pyrrolidin-2-one derivatives as intermediates in the synthesis of renin inhibitors NOVARTIS AG (CH) 2010-08-10 US disclosed
US-20080262246-A1 3-Alkyl-5- (4-Alkyl-5-Oxo-Tetrahydrofutr An -2-Yl) Pyrrolidin-2-One Derivatives As Intermediates In The Synthesis Of Renin Inhibitors NODEN PHARMA DESIGNATED ACTIVITY COMPANY (IE) 2008-10-23 US disclosed
EP-1966127-A1 CARBONYL ASYMMETRIC ALKYLATION Sandoz AG (CH) 2008-09-10 EP disclosed
US-20080210858-A1 High Stability Polyionic Liquid Salts SIGMA-ALDRICH CO. NEWCO INC. 2008-09-04 US disclosed
WO-2007082771-A1 CARBONYL ASYMMETRIC ALKYLATION SANDOZ AG (CH) 2007-07-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11241411-B2 Benzonatate modified release solid tablets and capsules SBDS, SI, BPGM KDM4E 1893/4885ALDH1A1 2102/4885AOC3 1929/4885
US-20080210858-A1 High Stability Polyionic Liquid Salts PUF60, POLI, PARG KDM4E 4398/4885ALDH1A1 4720/4885AOC3 4342/4885
US-20120083603-A1 HIGH STABILITY POLYIONIC LIQUID SALTS PUF60, POLI, PARG KDM4E 4398/4885ALDH1A1 4720/4885AOC3 4342/4885
US-20080262246-A1 3-Alkyl-5- (4-Alkyl-5-Oxo-Tetrahydrofutr An -2-Yl) Pyrrolidin-2-One Derivatives As Intermediates In The Synthesis Of Renin Inhibitors REN, AGTR2, AGTR1 KDM4E 789/4885ALDH1A1 1161/4885AOC3 324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.