Methylephedrine

Methylephedrine

SCHEMBL99674

CC(C(O)c1ccccc1)N(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 1.00
ALDH1A1 P00352 2/20 1.00
AOC3 Q16853 5/20 0.70
GAA P10253 1/20 0.56
ADRA2C P18825 2/20 0.56
ADRA2A P08913 1/20 0.56
LMNA P02545 1/20 0.56
HIF1A Q16665 1/20 0.56
CHRM2 P08172 1/20 0.52
ADRA1A P35348 1/20 0.52
RGS12 O14924 1/20 0.52
GLA P06280 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2D6 P10635 1/20 0.52
CYP2C9 P11712 1/20 0.52
PKM P14618 1/20 0.52
ALOX15 P16050 1/20 0.52
TSHR P16473 1/20 0.52
ALOX12 P18054 1/20 0.52
NFKB1 P19838 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylephedrine SCHEMBL907777 1.00 KDM4E (1.00) KDM4EALDH1A1AOC3GAAADRA2C
Methylephedrine SCHEMBL7496690 1.00 KDM4E (1.00) KDM4EALDH1A1AOC3GAAADRA2C
Methylephedrine SCHEMBL338479 1.00 KDM4E (1.00) KDM4EALDH1A1AOC3GAAADRA2C
Methylephedrine SCHEMBL2712293 1.00 KDM4E (1.00) KDM4EALDH1A1AOC3GAAADRA2C
Methylephedrine SCHEMBL11959977 1.00 KDM4E (1.00) KDM4EALDH1A1AOC3GAAADRA2C
Methylephedrine SCHEMBL907677 1.00 KDM4E (1.00) KDM4EALDH1A1AOC3GAAADRA2C
Methylephedrine SCHEMBL338478 1.00 KDM4E (1.00) KDM4EALDH1A1AOC3GAAADRA2C
Methylephedrine SCHEMBL99673 1.00 KDM4E (1.00) KDM4EALDH1A1AOC3GAAADRA2C
Methylephedrine SCHEMBL8083321 0.98 KDM4E (0.96) KDM4EALDH1A1AOC3GAAADRA2C
Methylephedrine SCHEMBL68363 0.98 ALDH1A1 (0.96) KDM4EALDH1A1AOC3GAAADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3520 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111212843-B Boric acid derivatives and synthesis thereof QPEX生物制药有限公司 2025-05-16 CN claimed
EP-3694864-B1 BORONIC ACID DERIVATIVES AND SYNTHESIS THEREOF QPEX BIOPHARMA INC (US) 2025-03-05 EP claimed
WO-2024040267-A2 DIRECT SYNTHESIS OF N-(3-SUBSTITUTED-CHROMAN-4-YL)-7H- PYRROLO[2,3-D]PYRIMIDIN-4-AMINES AND DERIVATIVES THEREOF MITOKININ, INC. (US) 2024-02-22 WO claimed
CN-113621133-B Reversible plasticizing type polyester chip and preparation method thereof 扬州帅帅高分子科技有限公司 2023-03-14 CN claimed
US-11286270-B2 Boronic acid derivatives and synthesis thereof QPEX BIOPHARMA, INC. (US) 2022-03-29 US claimed
CN-113621133-A Reversible plasticizing type polyester chip and preparation method thereof 扬州帅帅高分子科技有限公司 2021-11-09 CN claimed
CN-107001221-B Method for preparing treprostinil 奇诺因药物和化学工厂私人有限公司 2021-05-25 CN claimed
US-20200407373-A1 BORONIC ACID DERIVATIVES AND SYNTHESIS THEREOF QPEX BIOPHARMA, INC. 2020-12-31 US claimed
EP-3257841-B1 SYNTHESIS PROCESS FOR CHIRAL CYCLOPROPYL ETHYNYL TERTIARY ALCOHOL COMPOUND SHANGHAI DESANO PHARMACEUTICAL CO LTD (CN) 2020-07-08 EP claimed
CN-107513058-B TGIC curing agent for high temperature resistant field and preparation method thereof 黄山华惠科技有限公司 2020-03-27 CN claimed
EP-0035355-B1 MODIFIED ALUMINIUM HYDRIDES, THEIR PREPARATION AND THEIR USE IN REDUCING ACETYLNAPHTHALENE DERIVATIVES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-05-09 EP claimed
US-4418218-A REDUCTION WITH LITHIUM ALUMINUM HYDRIDE AND N-SUBSTITUTED EPHEDRINE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-11-29 US claimed
US-4338255-A Modified lithium aluminum hydrides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-07-06 US claimed
US-4335057-A 4-(2',2,2'-Trihalogenoethyl)-cyclobutane-1-sulfonic acid salts with optically active bases CIBA-GEIGY CORPORATION (US) 1982-06-15 US claimed
US-4328173-A Resolution of D,L-cis and D,L-trans 2,2-dimethyl-3-(2,2-dihalovinyl)-cyclopropane-1-carboxylic acids and salts thereof ROUSSEL UCLAF (FR) 1982-05-04 US claimed
US-4299967-A Process for producing optically active 2-(2,2-dihalogenovinyl)-cyclopropane-1-carboxylic acids substituted in the 3-position, and derivatives thereof, as well as novel 4-(2,2,2-trihalogenoethyl)-cyclobutane-1-sulfonic acid salts CIBA-GEIGY CORPORATION (US) 1981-11-10 US claimed
EP-0035355-A2 Modified aluminium hydrides, their preparation and their use in reducing acetylnaphthalene derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-09-09 EP claimed
US-4285884-A Process for resolution of racemic DL-α-aminocarboxylic acids RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1981-08-25 US claimed
EP-0001821-B1 RESOLUTION OF D,L-ALPHA-AMINO ACIDS AND SALTS USED THEREFOR RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1981-04-29 EP claimed
US-4257976-A SALT FORMATION WITH CHRYSANTHEMIC ACID ROUSSEL UCLAF (FR) 1981-03-24 US claimed