Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | RGS12 | O14924 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylephedrine SCHEMBL99674 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1AOC3GAAADRA2C | |
| Methylephedrine SCHEMBL907777 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1AOC3GAAADRA2C | |
| Methylephedrine SCHEMBL7496690 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1AOC3GAAADRA2C | |
| Methylephedrine SCHEMBL338479 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1AOC3GAAADRA2C | |
| Methylephedrine SCHEMBL2712293 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1AOC3GAAADRA2C | |
| Methylephedrine SCHEMBL11959977 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1AOC3GAAADRA2C | |
| Methylephedrine SCHEMBL338478 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1AOC3GAAADRA2C | |
| Methylephedrine SCHEMBL99673 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1AOC3GAAADRA2C | |
| Methylephedrine SCHEMBL8083321 | 0.98 | KDM4E (0.96) | KDM4EALDH1A1AOC3GAAADRA2C | |
| Methylephedrine SCHEMBL68363 | 0.98 | ALDH1A1 (0.96) | KDM4EALDH1A1AOC3GAAADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1314333-A | Method for asymmetrically synthesizing secondary propiolic alcohol compound | SHANGHAI INST ORGANIC CHEM (CN) | 2001-09-26 | — | — | CN | claimed |
| WO-2019113312-A1 | ANTICANCER COMPOUND PROCESS | INNOCRIN PHARMACEUTICALS, INC. (US) | 2019-06-13 | — | — | WO | disclosed |
| CN-105164131-A | Tricyclic heterocycles as bet protein inhibitors | INCYTE CORP | 2015-12-16 | — | — | CN | disclosed |
| CN-102203068-B | Cyclohexane derivative and pharmaceutical use thereof | TORAY INDUSTRIES | 2014-03-19 | — | — | CN | disclosed |
| CN-102906169-A | Nanoporous foaming formulations containing active ingredients based on pharmaceutically acceptable thermoplastically processable polymers | BASF SE | 2013-01-30 | — | — | CN | disclosed |
| US-8288569-B2 | Carbonyl asymmetric alkylation | SANDOZ AG (CH) | 2012-10-16 | — | — | US | disclosed |
| CN-102203068-A | Cyclohexane derivative and pharmaceutical use thereof | TORAY INDUSTRIES | 2011-09-28 | — | — | CN | disclosed |
| EP-1966127-B1 | CARBONYL ASYMMETRIC ALKYLATION | SANDOZ AG (CH) | 2011-04-06 | — | — | EP | disclosed |
| US-20110009648-A1 | Carbonyl Asymmetric Alkylation | SANDOZ AG (CH) | 2011-01-13 | — | — | US | disclosed |
| CN-100582092-C | Process for preparing diphenyl azetidinone derivatives | AVENTIS PHARMA GMBH | 2010-01-20 | — | — | CN | disclosed |
| EP-1966127-A1 | CARBONYL ASYMMETRIC ALKYLATION | Sandoz AG (CH) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007082771-A1 | CARBONYL ASYMMETRIC ALKYLATION | SANDOZ AG (CH) | 2007-07-26 | — | — | WO | disclosed |
| CN-1956951-A | Method for producing diphenyl azetidinone derivatives | AVENTIS PHARMA GMBH (DE) | 2007-05-02 | — | — | CN | disclosed |
| CN-1197836-C | Method for asymmetrically synthesizing secondary propiolic alcohol compound | SHANGHAI INST ORGANIC CHEM (CN) | 2005-04-20 | — | — | CN | disclosed |
| CN-1112355-C | Difluore methane-sulfonic acid metal reagent, and its synthetic method and use | SHANGHAI INST ORGANIC CHEM (CN) | 2003-06-25 | — | — | CN | disclosed |
| CN-1314344-A | Difluore methane-sulfonic acid metal reagent, and its synthetic method and use | SHANGHAI INST ORGANIC CHEM (CN) | 2001-09-26 | — | — | CN | disclosed |
| CN-1314333-A | Method for asymmetrically synthesizing secondary propiolic alcohol compound | SHANGHAI INST ORGANIC CHEM (CN) | 2001-09-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009648-A1 | Carbonyl Asymmetric Alkylation | COASY, ADH5, SI | KDM4E 880/4885ALDH1A1 53/4885AOC3 345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.