Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.40 |
| ▸ | ADAM33 | Q9BZ11 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7502501 | 0.85 | LTA4H (0.50) | LTA4HPSMB1PSMB5PSMB2HRH3 | |
| SCHEMBL7759793 | 0.80 | HRH3 (0.42) | LTA4HHRH3KMT2AGRM2 | |
| SCHEMBL7503034 | 0.80 | RAB9A (0.52) | PSMB1PSMB5PSMB2HRH3RAB9A | |
| Hydrochloric Acid SCHEMBL5708509 | 0.79 | HRH3 (0.41) | LTA4HHRH3KMT2AGRM2 | |
| SCHEMBL8164751 | 0.74 | POLB (0.42) | LTA4HHRH3KMT2ASLC6A4 | |
| SCHEMBL1986255 | 0.74 | MAPT (0.36) | LTA4HPSMB1PSMB5HRH3KMT2A | |
| SCHEMBL6731066 | 0.74 | SIGMAR1 (0.43) | HRH3RAB9AKMT2A | |
| SCHEMBL4322787 | 0.74 | CHRNB4 (0.47) | LTA4HKMT2A | |
| SCHEMBL14966522 | 0.74 | CHRNB4 (0.47) | LTA4HKMT2A | |
| SCHEMBL13712250 | 0.74 | ALDH1A3 (0.56) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763022-A1 | PHENOXYALKYL SUBSTITUTED PIPERIDINES, PYRROLIDINES, MORPHOLINES AND THIOMORPHOLINES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1997-03-19 | — | — | EP | claimed |
| WO-1995033723-A1 | PHENOXYALKYL SUBSTITUTED PIPERIDINES, PYRROLIDINES, MORPHOLINES AND THIOMORPHOLINES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-12-14 | — | — | WO | claimed |