SCHEMBL75023

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14473517	0.97	THRB (0.46)	THRBTSHRALDH1A1PEPDTP53
	SCHEMBL73761	0.97	THRB (0.46)	THRBTSHRALDH1A1PEPDTP53
	SCHEMBL194104	0.91	TSHR (0.50)	THRBTSHRALDH1A1TP53CYP3A4
	SCHEMBL195287	0.91	TSHR (0.46)	THRBTSHRALDH1A1PEPDTP53
	SCHEMBL208911	0.90	THRB (0.52)	THRBTSHRALDH1A1TP53CYP3A4
	SCHEMBL12192405	0.89	TSHR (0.53)	THRBTSHRALDH1A1TP53CYP3A4
	SCHEMBL17531129	0.88	THRB (0.44)	THRBTSHRALDH1A1PEPDPOLB
	SCHEMBL17531104	0.86	THRB (0.42)	THRBTSHRALDH1A1TP53CYP3A4
	SCHEMBL12192407	0.85	THRB (0.43)	THRBTSHRALDH1A1TP53CYP3A4
	SCHEMBL12270969	0.85	THRB (0.41)	THRBTSHRALDH1A1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.