SCHEMBL194104

SCHEMBL194104

C=C(C)C(=O)OCCCCOC(=O)C1CCCCC1C(=O)O

nearest known ligand 0.76

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
HTT P42858 2/20 0.43
POLB P06746 1/20 0.43
APEX1 P27695 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
THRB P10828 1/20 0.40
ALDH1A1 P00352 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
FKBP1A P62942 1/20 0.34
KDM4E B2RXH2 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12192405 0.98 TSHR (0.53) TSHRHTTPOLBAPEX1TDP1
SCHEMBL195287 0.97 TSHR (0.46) TSHRHTTPOLBAPEX1TDP1
SCHEMBL14473517 0.94 THRB (0.46) TSHRHTTPOLBAPEX1TDP1
SCHEMBL73761 0.94 THRB (0.46) TSHRHTTPOLBAPEX1TDP1
SCHEMBL422110 0.94 TSHR (0.56) TSHRHTTPOLBAPEX1TDP1
SCHEMBL75023 0.91 THRB (0.46) TSHRHTTPOLBAPEX1TDP1
SCHEMBL422679 0.91 TSHR (0.51) TSHRHTTPOLBAPEX1TDP1
SCHEMBL11618530 0.88 TSHR (0.41) TSHRHTTPOLBAPEX1TDP1
SCHEMBL208911 0.87 THRB (0.52) TSHRHTTPOLBAPEX1TDP1
SCHEMBL10715842 0.87 TP53 (0.47) ALDH1A1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230142648-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2023-05-11 US disclosed
EP-4114825-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2023-01-11 EP disclosed
US-20220121113-A1 OXIME ESTER PHOTOINITIATORS HAVING A SPECIAL AROYL CHROMOPHORE BASF SE (DE) 2022-04-21 US disclosed
US-11209733-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
US-11209734-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
EP-3044208-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2021-12-22 EP disclosed
US-11204554-B2 Oxime ester photoinitiators BASF SE 2021-12-21 US disclosed
EP-3914965-A1 OXIME ESTER PHOTOINITIATORS HAVING A SPECIAL AROYL CHROMOPHORE BASF SE (DE) 2021-12-01 EP disclosed
WO-2021175855-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2021-09-10 WO disclosed
US-10793555-B2 Oxime ester photoinitiators BASF SE (DE) 2020-10-06 US disclosed
WO-2006037728-A1 USE OF PYRIMIDO[5,4-G]PTERIDINES AS SHADING COMPONENT IN COLOR FILTER COLORANT COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-04-13 WO disclosed
WO-2006024617-A1 COMPOSITIONS CONTAINING ANTHRAQUINONE DYES HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2006-03-09 WO disclosed
WO-2006024619-A1 COMPOSITIONS CONTAINING PHTHALOCYANINE DYES HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2006-03-09 WO disclosed
WO-2006024618-A1 CYANOPYRIDINE-BASED AZO DYES HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2006-03-09 WO disclosed
WO-2006018405-A1 OXIME ESTER PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-02-23 WO disclosed
EP-1567518-A2 OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS Ciba SC Holding AG (CH) 2005-08-31 EP disclosed
WO-2004050653-A2 OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-06-17 WO disclosed
US-6602643-B2 Useful as a protective material for etching, as back-coating material in the production of a shadow mask TAIYO INK MANUFACTURING CO., LTD. (JP) 2003-08-05 US disclosed
US-20020146629-A1 Ultraviolet-curable resin composition TAIYO INK MANUFACTURING CO., LTD. (JP) 2002-10-10 US disclosed
EP-1219680-A1 ULTRAVIOLET-CURABLE RESIN COMPOSITION Taiyo Ink Manufacturing Co. Ltd (JP) 2002-07-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11209734-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 TSHR 528/4885HTT 3946/4885POLB 961/4885
US-11204554-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 TSHR 519/4885HTT 4008/4885POLB 963/4885
US-10793555-B2 Oxime ester photoinitiators NR2E3, OXER1, CBR3 TSHR 310/4885HTT 4054/4885POLB 1874/4885
US-11209733-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 TSHR 528/4885HTT 3946/4885POLB 961/4885
US-20230142648-A1 OXIME ESTER PHOTOINITIATORS OCIAD1, OCIAD2, OXER1 TSHR 2202/4885HTT 3765/4885POLB 1333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.