Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 2/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11409795 | 0.82 | LTA4H (0.38) | TSHRLTA4H | |
| Diphenylether SCHEMBL28706414 | 0.76 | LTA4H (0.60) | POLBGAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2034789 | 0.76 | GAA (0.41) | POLBGAASMN1; SMN2TSHRKDM4E | |
| SCHEMBL983525 | 0.73 | TSHR (0.44) | GAAKMT2ATSHRLTA4HHPGD | |
| SCHEMBL7803639 | 0.72 | LTA4H (0.43) | POLBSMN1; SMN2TSHRLTA4HHPGD | |
| SCHEMBL6036733 | 0.72 | LTA4H (0.42) | POLBGAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11140990 | 0.72 | LTA4H (0.42) | KMT2ATSHRLTA4HHPGDKDM4E | |
| SCHEMBL422932 | 0.72 | MAOA (0.43) | GAAMEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL4932041 | 0.72 | LTA4H (0.42) | TSHRLTA4HHPGDL3MBTL1 | |
| SCHEMBL11141243 | 0.72 | LTA4H (0.42) | KMT2ATSHRLTA4HKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399731-B2 | SYNTHESIZING POLYMERS USING PHOSPHOROUS-CONTAINING ADDITION-FRAGMENTATION CHAIN TRANSFER AGENTS; MOLECULAR WEIGHT CONTROL | THE UNIVERSITY OF AKRON | 2002-06-04 | — | — | US | disclosed |
| US-20020016424-A1 | Synthesizing polymers using phosphorous-containing addition-fragmentation chain transfer agents; molecular weight control | AKRON, THE UNIVERSITY OF | 2002-02-07 | — | — | US | disclosed |
| WO-2000020465-A1 | NOVEL CHAIN TRANSFER AGENTS | THE UNIVERSITY OF AKRON (US) | 2000-04-13 | — | — | WO | disclosed |