Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.36 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7227304 | 0.83 | MGLL (0.42) | LMNAALDH1A1KMT2ATSHRL3MBTL1 | |
| SCHEMBL11035688 | 0.83 | LMNA (0.39) | GAALMNAALDH1A1KMT2ACYP1A2 | |
| SCHEMBL11325537 | 0.81 | GAA (0.44) | GAALMNAALDH1A1KMT2ACYP1A2 | |
| SCHEMBL7913963 | 0.81 | LMNA (0.38) | LMNAALDH1A1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL5712943 | 0.79 | MEN1 (0.53) | GAALMNAALDH1A1KMT2ATSHR | |
| SCHEMBL9568054 | 0.77 | CA9 (0.41) | GAALMNAALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL4395920 | 0.75 | L3MBTL1 (0.44) | GAALMNAALDH1A1KMT2AHTT | |
| SCHEMBL5382585 | 0.74 | PPOX (0.44) | LMNAALDH1A1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL8163464 | 0.72 | ALPL (0.33) | ALDH1A1SMN1; SMN2TSHRPOLBMAPT | |
| SCHEMBL9599660 | 0.70 | LMNA (0.32) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1030843-A4 | SUBSTITUTED BENZENE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND HERBICIDAL AND DEFOLIANT COMPOSITIONS CONTAINING THEM | ISK AMERICAS INC (US) | 2002-11-06 | — | — | EP | disclosed |
| EP-1030843-A1 | SUBSTITUTED BENZENE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND HERBICIDAL AND DEFOLIANT COMPOSITIONS CONTAINING THEM | ISK Americas Incorporated (US) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999021837-A1 | SUBSTITUTED BENZENE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND HERBICIDAL AND DEFOLIANT COMPOSITIONS CONTAINING THEM | ISK AMERICAS INCORPORATED (US) | 1999-05-06 | — | — | WO | disclosed |