SCHEMBL7513504

SCHEMBL7513504

Cc1cccc(S(=O)(=O)c2nc(-c3ccccc3)ns2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.42
ADORA3 P0DMS8 2/20 0.41
RXFP1 Q9HBX9 1/20 0.41
MAPT P10636 2/20 0.41
ADORA2A P29274 1/20 0.41
ADORA2B P29275 1/20 0.41
ADORA1 P30542 1/20 0.41
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 1/20 0.40
GLA P06280 1/20 0.40
GAA P10253 1/20 0.40
HPGD P15428 1/20 0.40
PTPN2 P17706 1/20 0.40
PTPN1 P18031 1/20 0.40
PTPN5 P54829 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
FFAR2 O15552 1/20 0.39
PKM P14618 1/20 0.39
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7214866 0.85 ADORA3 (0.50) ADORA3ADORA2AADORA2BADORA1ALDH1A1
SCHEMBL8075141 0.84 ADORA3 (0.50) ADORA3RXFP1MAPTADORA2AADORA2B
SCHEMBL14755635 0.82 ADORA3 (0.48) ADORA3RXFP1MAPTADORA2AADORA2B
SCHEMBL14755599 0.76 GAA (0.48) ADORA3RXFP1MAPTALDH1A1GAA
SCHEMBL9869306 0.75 RAB9A (0.49) FAAHMAPTALDH1A1HPGDSMN1; SMN2
SCHEMBL7697006 0.75 ADORA3 (0.44) FAAHADORA3RXFP1MAPTADORA2A
SCHEMBL7695561 0.74 ADORA3 (0.52) ADORA3RXFP1MAPTADORA2AADORA2B
SCHEMBL28393143 0.73 HSD17B1 (0.57) FAAHADORA3RXFP1MAPTADORA2A
SCHEMBL14755634 0.73 CTRC (0.44) RXFP1ALDH1A1KDM4EGAAHPGD
SCHEMBL7513505 0.73 SMN1; SMN2 (0.41) FAAHADORA3RXFP1MAPTADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0863886-B1 FLUOROMETHOXYACRYLIC ACID DERIVATIVES AND THEIR USE AS PEST CONTROL AGENTS BAYER AG (DE) 2002-01-09 EP disclosed
US-6337401-B1 MULTISTAGE REACTION OF AROMATIC FORMIC ACID DERIVATIVE IN THE PRESENCE OF A BASIC CATALYST TO FORM ENOL AND REACTION WITH BROMOFLUOROMETHANE AND FLUOROCHLOROMETHANE BAYER AKTIENGESELLSCHAFT (DE) 2002-01-08 US disclosed
EP-1061066-A2 Fluoromethoxyacrylic acid derivatives, intermediates in the preparation of pest control agents BAYER AG (DE) 2000-12-20 EP disclosed
US-6031107-A Fluoromethoxyacrylic acid derivatives and their use as pest control agents BAYER AKTIENGESELLSCHAFT (DE) 2000-02-29 US disclosed
EP-0863886-A1 FLUOROMETHOXYACRYLIC ACID DERIVATIVES AND THEIR USE AS PEST CONTROL AGENTS BAYER AG (DE) 1998-09-16 EP disclosed
WO-1997014687-A1 FLUOROMETHOXYACRYLIC ACID DERIVATIVES AND THEIR USE AS PEST CONTROL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1997-04-24 WO disclosed