SCHEMBL7214866

SCHEMBL7214866

O=S(=O)(c1ccccc1)c1nc(-c2ccccc2)ns1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 5/20 0.50
ADORA2A P29274 1/20 0.50
ADORA2B P29275 1/20 0.50
ADORA1 P30542 1/20 0.50
HTR6 P50406 1/20 0.45
NPC1 O15118 4/20 0.45
RAB9A P51151 4/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
CASP3 P42574 1/20 0.45
SENP8 Q96LD8 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
SENP6 Q9GZR1 1/20 0.45
SMN1; SMN2 Q16637 4/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
ALDH1A1 P00352 4/20 0.43
KDM4E B2RXH2 3/20 0.43
PKM P14618 1/20 0.43
NPSR1 Q6W5P4 2/20 0.41
PIK3CA P42336 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8075141 0.89 ADORA3 (0.50) ADORA3ADORA2AADORA2BADORA1MEN1
SCHEMBL14755635 0.86 ADORA3 (0.48) ADORA3ADORA2AADORA2BADORA1MEN1
SCHEMBL7513504 0.85 FAAH (0.42) ADORA3ADORA2AADORA2BADORA1KMT2A
SCHEMBL9867067 0.80 ADORA3 (0.56) ADORA3ADORA2AADORA2BADORA1NPC1
SCHEMBL6563769 0.80 ADORA3 (0.52) ADORA3ADORA2AADORA2BADORA1NPC1
SCHEMBL7695561 0.80 ADORA3 (0.52) ADORA3ADORA2AADORA2BADORA1NPC1
SCHEMBL14755599 0.79 GAA (0.48) ADORA3NPC1RAB9AMEN1KMT2A
SCHEMBL7697006 0.79 ADORA3 (0.44) ADORA3ADORA2AADORA2BADORA1NPC1
SCHEMBL3482423 0.79 HTR6 (0.45) HTR6KMT2ASMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL7513501 0.75 ADORA3 (0.46) ADORA3ADORA2AADORA2BADORA1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6632817-B2 Use as pesticides such as 2-fluoromethoxyimino-N-methyl-2-((6-aryl-s-triazin-2-yloxy)-phenyl) -acetamide; use on crops as fungicide; microbiocide on wood; chemical synthesis BAYER AG (DE) 2003-10-14 US disclosed
US-20020028811-A1 Use as pesticides such as 2-fluoromethoxyimino-N-methyl-2-((6-aryl-s-triazin-2-yloxy)-phenyl) -acetamide; use on crops as fungicide; microbiocide on wood; chemical synthesis HEINEMANN ULRICH (DE) 2002-03-07 US disclosed
US-6306855-B1 PESTICIDES, AND ALSO TO NOVEL INTERMEDIATES AND TO A PLURALITY OF PROCESSES FOR THEIR PREPARATION. BAYER AKTIENGESELLSCHAFT (DE) 2001-10-23 US disclosed
EP-0986542-A1 FLUOROMETHOXIMINO COMPOUNDS Bayer Aktiengesellschaft (DE) 2000-03-22 EP disclosed
WO-1998055461-A1 FLUOROMETHOXIMINO COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1998-12-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020028811-A1 Use as pesticides such as 2-fluoromethoxyimino-N-methyl-2-((6-aryl-s-triazin-2-yloxy)-phenyl) -acetamide; use on crops as fungicide; microbiocide on wood; chemical synthesis PFAS, DDT, DNPH1 ADORA3 1382/4885ADORA2A 1563/4885ADORA2B 2753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.