Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 6/20 | 0.49 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | CAPNS1 | P04632 | 1/20 | 0.44 |
| ▸ | CCKBR | P32239 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 2/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7515201 | 0.88 | CAPN1 (0.59) | CAPN1CCR1CAPNS1 | |
| SCHEMBL7510995 | 0.87 | CAPN1 (0.49) | CAPN1CCR1CAPNS1CCKBRMC4R | |
| SCHEMBL7514607 | 0.83 | CAPN1 (0.49) | CAPN1CCR1 | |
| SCHEMBL7513532 | 0.75 | CAPN1 (0.61) | CAPN1CCR1CAPNS1 | |
| SCHEMBL7514977 | 0.75 | CAPN1 (0.59) | CAPN1CAPNS1 | |
| SCHEMBL7514986 | 0.74 | CAPN1 (0.52) | CAPN1CAPNS1 | |
| SCHEMBL8812581 | 0.74 | CTSK (0.60) | CAPN1 | |
| SCHEMBL8812573 | 0.74 | CTSK (0.60) | CAPN1 | |
| SCHEMBL8812460 | 0.73 | CASP1 (0.72) | CAPN1CAPNS1 | |
| SCHEMBL8812453 | 0.73 | CASP1 (0.72) | CAPN1CAPNS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641800-B1 | Lactol derivatives as inhibitors of cathepsin L | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-01-16 | — | — | EP | claimed |
| EP-0641800-B1 | Lactol derivatives as inhibitors of cathepsin L | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-01-16 | — | — | EP | disclosed |