Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 14/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CAPNS1 | P04632 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810989 | 0.89 | CAPN1 (0.75) | CAPN1CAPNS1 | |
| SCHEMBL8812573 | 0.82 | CTSK (0.60) | CAPN1 | |
| SCHEMBL8812581 | 0.82 | CTSK (0.60) | CAPN1 | |
| SCHEMBL27427437 | 0.80 | CTSS (0.56) | CAPN1 | |
| SCHEMBL7516532 | 0.80 | CTSS (0.56) | CAPN1 | |
| SCHEMBL7514986 | 0.80 | CAPN1 (0.52) | CAPN1ALDH1A1CAPNS1 | |
| SCHEMBL7517586 | 0.80 | CAPN1 (0.54) | CAPN1CAPNS1 | |
| SCHEMBL7514607 | 0.77 | CAPN1 (0.49) | CAPN1ALDH1A1 | |
| SCHEMBL7514760 | 0.75 | CAPN1 (0.49) | CAPN1CAPNS1 | |
| SCHEMBL4972757 | 0.74 | CAPN1 (1.00) | CAPN1CAPNS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641800-B1 | Lactol derivatives as inhibitors of cathepsin L | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-01-16 | — | — | EP | claimed |
| EP-0641800-B1 | Lactol derivatives as inhibitors of cathepsin L | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-01-16 | — | — | EP | disclosed |