Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.41 |
| ▸ | PGR | P06401 | 4/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7515798 | 0.93 | L3MBTL1 (0.40) | L3MBTL1KIF11NR3C1PGRNR3C2 | |
| SCHEMBL4821971 | 0.76 | F2 (0.43) | L3MBTL1NR3C1PGRNR3C2LMNA | |
| SCHEMBL4746886 | 0.69 | NR3C1 (0.36) | L3MBTL1NR3C1PGRNR3C2MAPT | |
| SCHEMBL7523376 | 0.68 | KEAP1 (0.39) | L3MBTL1KIF11FFAR4MAPTKCNN4 | |
| SCHEMBL7525267 | 0.68 | KEAP1 (0.39) | L3MBTL1KIF11FFAR4MAPTKCNN4 | |
| SCHEMBL7513698 | 0.68 | KEAP1 (0.38) | L3MBTL1KIF11FFAR4MAPTKCNN4 | |
| SCHEMBL15841552 | 0.65 | L3MBTL1 (0.57) | L3MBTL1NR3C1PGRNR3C2FFAR4 | |
| SCHEMBL2547809 | 0.64 | KIF11 (0.46) | KIF11CYP1A2CYP2C19KCNN4SMN1; SMN2 | |
| SCHEMBL22361680 | 0.64 | KIF11 (0.61) | KIF11 | |
| SCHEMBL14935909 | 0.64 | KIF11 (0.61) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020045780-A1 | Biologically active spermidine analogues, pharmaceutical compositions and methods of treatment | BERGERON RAYMOND J (US) | 2002-04-18 | — | — | US | disclosed |
| US-6235794-B1 | ANTICANCER AGENT | UNIVERSITY OF FLORIDA | 2001-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020045780-A1 | Biologically active spermidine analogues, pharmaceutical compositions and methods of treatment | SRM, SLC7A1, CATSPER1 | L3MBTL1 3921/4885KIF11 4301/4885NR3C1 1332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.