Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9473446 | 0.80 | TSHR (0.31) | TSHRSMN1; SMN2 | |
| SCHEMBL239869 | 0.79 | LMNA (0.33) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL19743670 | 0.79 | FAAH (0.48) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL8823424 | 0.79 | ALDH1A1 (0.33) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL8480017 | 0.79 | CA2 (0.48) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL1987184 | 0.78 | PSIP1 (0.34) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL692150 | 0.77 | APP (0.33) | CA2 | |
| SCHEMBL3097610 | 0.76 | PSIP1 (0.47) | TSHRSMN1; SMN2 | |
| SCHEMBL8954134 | 0.76 | MGLL (0.35) | — | |
| SCHEMBL8474314 | 0.75 | CA1 (0.36) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101855225-B | Tricyclic bridged cyclopentanedione derivatives as herbicides | SYNGENTA LTD | 2014-01-08 | — | — | CN | disclosed |
| CN-102348686-A | Bis aromatic compounds for use as ltc4 synthase inhibitors | BIOLIPOX AB (SE) | 2012-02-08 | — | — | CN | disclosed |
| CN-101855225-A | Tricyclic bridged cyclopentanedione derivatives as weedicide | SYNGENTA LTD | 2010-10-06 | — | — | CN | disclosed |
| CN-1889940-A | Treatment of personality changes due to hot flashes, impulse control disorders and systemic medical conditions | LILLY CO ELI (US) | 2007-01-03 | — | — | CN | disclosed |
| EP-1263804-A1 | REACTIVE POLYMERS | Novartis AG (CH) | 2002-12-11 | — | — | EP | disclosed |
| EP-1169366-A1 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2002-01-09 | — | — | EP | disclosed |
| WO-2001066605-A1 | REACTIVE POLYMERS | NOVARTIS AG (CH) | 2001-09-13 | — | — | WO | disclosed |
| WO-2000059970-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2000-10-12 | — | — | WO | disclosed |
| CN-1046942-C | Imidazopyridines | MERCK PATENT GMBH (DE) | 1999-12-01 | — | — | CN | disclosed |
| US-5672738-A | REACTING AN AROMATIC SUBSTITUTED CYCLIC CARBAMATE WITH 2-MERCAPTETHANOL IN PRESENCE OF A BASIC CATALYST | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-30 | — | — | US | disclosed |
| CN-1129702-A | Imidazopyridines | MERCK PATENT GMBH (DE) | 1996-08-28 | — | — | CN | disclosed |
| US-5274086-A | A xanthene derivative | KIKKOMAN CORPORATION (JP) | 1993-12-28 | — | — | US | disclosed |
| EP-0114032-B1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1987-07-01 | — | — | EP | disclosed |
| EP-0074928-A2 | Reactive dyestuffs, their preparation and their use | CIBA-GEIGY AG (CH) | 1983-03-23 | — | — | EP | disclosed |