Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.42 |
| ▸ | ITGAV | P06756 | 4/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6857764 | 1.00 | MTNR1A (0.45) | MTNR1AMTNR1BHTR2AHSD17B1ITGB3 | |
| SCHEMBL6857996 | 1.00 | MTNR1A (0.45) | MTNR1AMTNR1BHTR2AHSD17B1ITGB3 | |
| SCHEMBL19984866 | 0.84 | CYP1A2 (0.49) | MTNR1AMTNR1BCYP1A2 | |
| SCHEMBL6643325 | 0.83 | ITGB3 (0.53) | MTNR1AMTNR1BHTR2AITGB3ITGAV | |
| SCHEMBL6642395 | 0.83 | ITGB3 (0.53) | MTNR1AMTNR1BHTR2AITGB3ITGAV | |
| SCHEMBL6646029 | 0.83 | ITGB3 (0.53) | MTNR1AMTNR1BHTR2AITGB3ITGAV | |
| SCHEMBL6862777 | 0.82 | MTNR1A (0.40) | MTNR1AMTNR1BHSD17B1ITGB3ITGAV | |
| SCHEMBL6862775 | 0.82 | MTNR1A (0.40) | MTNR1AMTNR1BHSD17B1ITGB3ITGAV | |
| SCHEMBL7442839 | 0.82 | SRD5A2 (0.44) | MTNR1AMTNR1BITGB3ITGAVITGB1 | |
| SCHEMBL6857908 | 0.81 | MTNR1A (0.38) | MTNR1AMTNR1BITGB3ITGAVITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020032187-A1 | Method for stimulating bone formation | SMITHKLINE BEECHAM CORPORATION | 2002-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032187-A1 | Method for stimulating bone formation | BMP2, BMP4, SOST | MTNR1A 603/4885MTNR1B 395/4885HTR2A 3511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.