Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL293213 | 0.80 | HTR3E (0.50) | MAPK1ALOX15MEN1KMT2ALMNA | |
| SCHEMBL7516695 | 0.77 | CHRNA7 (0.42) | CHRNA7CYP3A4MAPK1ALOX15HSD17B10 | |
| SCHEMBL6153220 | 0.75 | ALDH1A1 (0.66) | MAPK1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL13128200 | 0.75 | CHRNA7 (0.44) | CHRNA7CYP3A4MAPK1ALOX15HSD17B10 | |
| SCHEMBL576454 | 0.74 | LMNA (0.67) | CHRNA7CYP3A4MAPK1ALOX15HSD17B10 | |
| SCHEMBL576814 | 0.74 | LMNA (0.67) | CHRNA7CYP3A4MAPK1ALOX15HSD17B10 | |
| SCHEMBL385012 | 0.74 | — | — | |
| SCHEMBL164538 | 0.74 | LMNA (0.67) | CHRNA7CYP3A4MAPK1ALOX15HSD17B10 | |
| SCHEMBL16924853 | 0.74 | LMNA (0.67) | CHRNA7CYP3A4MAPK1ALOX15HSD17B10 | |
| SCHEMBL21623 | 0.73 | SMN1; SMN2 (0.50) | MAPK1HSD17B10KMT2ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625046-A | Hydroxyl projecting groups for organic synthesis | KING'S COLLEGE LONDON (GB) | 1997-04-29 | — | — | US | disclosed |
| US-5436331-A | Etherification with N-aryl-4-alkoxy-1,2,5,6-tetrahydropyidine | KINGS COLLEGE LONDON (GB) | 1995-07-25 | — | — | US | disclosed |
| EP-0298982-B1 | PROTECTING GROUPS FOR ORGANIC SYNTHESIS | KING'S COLLEGE LONDON (GB) | 1991-08-28 | — | — | EP | disclosed |