SCHEMBL75170

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL91175	0.92	KMT2A (0.46)	KMT2AATMELANESMN1; SMN2ALDH1A1
	SCHEMBL6934978	0.87	PGR (0.52)	KMT2AATMCTNNB1WNT3APGR
	SCHEMBL875456	0.81	CTNNB1 (0.51)	KMT2AATMCTNNB1WNT3APGR
	SCHEMBL12216202	0.81	CTNNB1 (0.45)	KMT2AATMCTNNB1WNT3APGR
	SCHEMBL19152417	0.80	KMT2A (0.46)	KMT2AATMCTNNB1WNT3AELANE
	SCHEMBL76679	0.78	KMT2A (0.47)	KMT2AATMELANESMN1; SMN2ALDH1A1
	SCHEMBL10448606	0.78	ALDH1A1 (0.45)	KMT2AATMELANESMN1; SMN2ALDH1A1
	SCHEMBL9479673	0.78	MAPT (0.52)	KMT2APGRSMN1; SMN2ALDH1A1MAPT
	SCHEMBL9920513	0.77	CTNNB1 (0.48)	KMT2ACTNNB1WNT3APGRALDH1A1
	SCHEMBL74946	0.77	GRM5 (0.49)	KMT2AATMELANESMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 456 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.