SCHEMBL76679

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL75400	0.89	KMT2A (0.47)	KMT2AATMMAOBMAOAELANE
	SCHEMBL76684	0.88	MAOA (0.60)	KMT2AATMMAOBMAOAELANE
	SCHEMBL23963404	0.81	MAOB (0.50)	KMT2AMAOBMAOAALDH1A1SMN1; SMN2
	SCHEMBL91175	0.81	KMT2A (0.46)	KMT2AATMELANEALDH1A1SMN1; SMN2
	SCHEMBL19335475	0.80	KDM4E (0.47)	KMT2AMAOBMAOAELANEALDH1A1
	SCHEMBL75279	0.80	MAOA (0.47)	KMT2AATMMAOBMAOAELANE
	SCHEMBL19718935	0.80	MAOA (0.47)	KMT2AMAOBMAOAELANEALDH1A1
	SCHEMBL75170	0.78	KMT2A (0.44)	KMT2AATMELANEALDH1A1SMN1; SMN2
	SCHEMBL783519	0.78	KMT2A (0.51)	KMT2AATMELANEALDH1A1SMN1; SMN2
	SCHEMBL30539317	0.77	CA2 (0.58)	KMT2AMAOBMAOAALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 469 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.